Health
Pig heart transplanted into human patient for the second time
Surgeons have transplanted a pig’s heart into a dying man in a bid to prolong his life – only the second patient to ever undergo such an experimental feat. Two days later, the man was cracking jokes and able to sit in a chair, Maryland doctors said Friday.
The 58-year-old Navy veteran was facing near-certain death from heart failure but other health problems meant he wasn’t eligible for a traditional heart transplant, according to doctors at University of Maryland Medicine, the Associated Press reported.
“Nobody knows from this point forward. At least now I have hope and I have a chance,” Lawrence Faucette, from Frederick, Maryland, said in a video recorded by the hospital before Wednesday’s operation. “I will fight tooth and nail for every breath I can take.”
While the next few weeks will be critical, doctors were thrilled at Faucette’s early response to the pig organ.
“You know, I just keep shaking my head – how am I talking to someone who has a pig heart?” Dr. Bartley Griffith, who performed the transplant, told The Associated Press. He said doctors are feeling “a great privilege but, you know, a lot of pressure.”
The same Maryland team last year performed the world’s first transplanet of a genetically modified pig heart into another dying man, David Bennett, who survived just two months.
There’s a huge shortage of human organs donated for transplant. Last year, there were just over 4,100 heart transplants in the U.S., a record number but the supply is so tight that only patients with the best chance of long-term survival get offered one.
Attempts at animal-to-human organ transplants have failed for decades, as people’s immune systems immediately destroyed the foreign tissue. Now scientists are trying again using pigs genetically modified to make their organs more humanlike.
Recently, scientists at other hospitals have tested pig kidneys and hearts in donated human bodies, hoping to learn enough to begin formal studies of what are called xenotransplants.
To make this new attempt in a living patient outside of a rigorous trial, the Maryland researchers required special permission from the Food and Drug Administration, under a process reserved for certain emergency cases with no other options.
It took over 300 pages of documents filed with FDA, but the Maryland researchers made their case that they’d learned enough from their first attempt last year – even though that patient died for reasons that aren’t fully understood – that it made sense to try again.
And Faucette, who retired as a lab technician at the National Institutes of Health, had to agree that he understood the procedure’s risks.
In a statement his wife, Ann Faucette, said: “We have no expectations other than hoping for more time together. That could be as simple as sitting on the front porch and having coffee together.”
What’s different this time: Only after last year’s transplant did scientists discover signs of a pig virus lurking inside the heart – and they now have better tests to look for hidden viruses. They also made some medication changes.
Possibly more important, while Faucette has end-stage heart failure and was out of other options, he wasn’t as near death as the prior patient.
By Friday, his new heart was functioning well without any supportive machinery, the hospital said.
“It’s just an amazing feeling to see this pig heart work in a human,” said Dr. Muhammad Mohiuddin, the Maryland team’s xenotransplantation expert. But, he cautioned, “we don’t want to predict anything. We will take every day as a victory and move forward.”
This kind of single-patient “compassionate use” can provide some information about how the pig organ works but not nearly as much as more formal testing, said Karen Maschke, a research scholar at the Hastings Center who is helping develop ethics and policy recommendations for xenotransplant clinical trials. That FDA allowed this second case “suggests that the agency is not ready to permit a pig heart clinical trial to start,” Mashke added.
The pig heart, provided by Blacksburg, Virginia-based Revivicor, has 10 genetic modifications – knocking out some pig genes and adding some human ones to make it more acceptable to the human immune system.
Health
EU considers restricting ethanol in hand sanitisers over cancer concerns
The recommendation has sparked debate among health experts and industry groups, as ethanol remains one of the most widely used disinfectants worldwide.
The European Union is weighing whether to classify ethanol — a key ingredient in most hand sanitisers and cleaning products — as a potentially dangerous substance linked to cancer and pregnancy complications.
According to a Financial Times report on Tuesday, an internal working group within the European Chemicals Agency (ECHA) recommended on October 10 that ethanol be listed as toxic, citing possible links to cancer risks.
The recommendation has sparked debate among health experts and industry groups, as ethanol remains one of the most widely used disinfectants worldwide.
The ECHA’s Biocidal Products Committee is expected to meet between November 25 and 28 to review the findings. If the committee concludes that ethanol is carcinogenic, it may recommend substituting the substance in cleaning and disinfectant products. The final decision, however, would rest with the European Commission.
The ECHA did not immediately respond to a request for comment, but told the Financial Times that no decision had yet been made. The agency noted that ethanol could still be approved for use in biocidal products if exposure levels are deemed safe or if suitable alternatives are unavailable.
The World Health Organization (WHO), meanwhile, continues to classify ethanol-based hand sanitisers as safe and effective for hand hygiene — a position that guided global health practices during the COVID-19 pandemic.
Any move to restrict ethanol could have major implications for manufacturers of disinfectants, cosmetics, and personal hygiene products across Europe, where ethanol-based formulations dominate the market.
Health
Toxic cough syrup claims lives of 14 children in India
According to health officials, the deaths occurred across three states — Madhya Pradesh, Rajasthan, and Tamil Nadu — with Madhya Pradesh reporting 11 fatalities.
At least 14 children have died in India after consuming a contaminated cough syrup, prompting multiple state bans and a nationwide investigation into the pharmaceutical manufacturer responsible.
According to health officials, the deaths occurred across three states — Madhya Pradesh, Rajasthan, and Tamil Nadu — with Madhya Pradesh reporting 11 fatalities.
Preliminary tests by India’s drug regulator found dangerous levels of toxic chemicals, believed to include diethylene glycol (DEG) or ethylene glycol, substances often associated with previous mass poisonings linked to poor-quality medicines.
Authorities have filed criminal charges against the company that produced the syrup, reportedly named Coldrif, citing adulteration and violations of the Drugs and Cosmetics Act.
A doctor alleged to have prescribed the syrup has also been detained as part of the investigation.
India’s Ministry of Health has ordered an immediate suspension of the product’s sale and distribution while samples are being tested at central laboratories. Officials said they are working to identify whether the tainted batch was distributed to other parts of the country or exported.
The tragedy has reignited concerns over India’s pharmaceutical safety standards.
Over the past three years, Indian-made cough syrups have been linked to child deaths in Gambia, Uzbekistan, and Cameroon, leading to international scrutiny of the country’s drug manufacturing practices.
Health experts have called for stricter enforcement and transparent testing to prevent similar incidents, warning that weak oversight continues to endanger lives, particularly in low-income regions where counterfeit or substandard medicines often circulate unchecked.
Health
Chronic illness and mental health challenges threaten millions across Afghanistan
In response, Afghanistan’s Ministry of Public Health approved a national health policy in March 2025 prioritizing NCD prevention, cancer care, and mental health.
Non-communicable diseases (NCDs) and mental health conditions are emerging as a hidden epidemic in Afghanistan, putting severe pressure on the country’s fragile health system.
According to a new report issued by the World Health Organization (WHO) on Sunday, heart disease, diabetes, cancer, and chronic lung conditions already account for 43% of deaths nationwide – a figure expected to rise above 60% by 2030, with women disproportionately affected.
Cardiovascular disease alone claims more than 40,000 lives each year, ranking Afghanistan among countries with the highest age-adjusted death rates globally.
Cancer, particularly breast and cervical cancer, also heavily impacts Afghan women, with many patients seeking care only at advanced stages when treatment options are limited.
Mental health meanwhile is increasingly recognized as a critical yet under-addressed concern, WHO reported.
Years of conflict, displacement, and natural disasters – including recent earthquakes – have left deep psychological scars, especially among families returning from Pakistan and Iran.
One in five Afghans is estimated to live with a mental health condition, with over half of returnee families affected by anxiety, depression, or post-traumatic stress last year.
Thousands of families face long waiting lists for treatment, particularly in rural areas.
Hospitals and primary health care facilities frequently lack dedicated mental health services, leaving vulnerable populations without care.
For families like that of Rahimi in eastern Afghanistan, the impact is deeply personal. A recent earthquake destroyed his home, disrupted his wife’s diabetes treatment, and left his teenage daughters struggling with anxiety.
“We survive the disasters, but the illness and worry never leave,” he said.
In response, Afghanistan’s Ministry of Public Health approved a national health policy in March 2025 prioritizing NCD prevention, cancer care, and mental health.
The World Health Organization (WHO) is working with authorities to expand access to care, strengthen community awareness, and provide targeted support for women and children.
“Millions across Afghanistan live with chronic illness and mental health challenges, placing enormous pressure on an already fragile system,” said Dr Edwin Ceniza Salvador, WHO Representative to Afghanistan.
“Beyond physical disease, trauma and psychological suffering continue to affect families and communities. Expanding access to care for both NCDs and mental health is a shared responsibility for WHO, health authorities, and donors.”
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