Health
U.S. man recovering after ‘breakthrough’ pig-heart transplant
A U.S. man with terminal heart disease was implanted with a genetically modified pig heart in a first-of-its-kind surgery, and three days later the patient is doing well, his doctors reported on Monday.
The surgery, performed by a team at the University of Maryland Medicine, is among the first to demonstrate the feasibility of a pig-to-human heart transplant, a field made possible by new gene editing tools, Reuters reported.
If proven successful, scientists hope pig organs could help alleviate shortages of donor organs.
“This was a breakthrough surgery and brings us one step closer to solving the organ shortage crisis. There are simply not enough donor human hearts available to meet the long list of potential recipients,” Dr. Bartley Griffith, who surgically transplanted the pig heart into the patient, said in a statement.
“We are proceeding cautiously, but we are also optimistic that this first-in-the-world surgery will provide an important new option for patients in the future,” Griffith added.
According to the report for 57-year-old David Bennett of Maryland, the heart transplant was his last option.
“It was either die or do this transplant. I want to live. I know it’s a shot in the dark, but it’s my last choice,” Bennett said a day before his surgery, according to a statement released by the university.
To move ahead with the experimental surgery, the university obtained an emergency authorization from the U.S. Food and Drug Administration on New Year’s Eve through its compassionate use program.
“The FDA used our data and data on the experimental pig to authorize the transplant in an end-stage heart disease patient who had no other treatment options,” said Dr. Muhammad Mohiuddin, who heads the University’s program on xenotransplantation – transplanting animal organs into humans.
About 110,000 Americans are currently waiting for an organ transplant, and more than 6,000 patients die each year before getting one, according to organdonor.gov.
Bennett’s genetically modified pig heart was provided by Revivicor, a regenerative medicine company based in Blacksburg, Virginia. On the morning of the surgery, the transplant team removed the pig’s heart and placed it into a special device to preserve its function until the surgery, read the report.
Pigs have long been a tantalizing source of potential transplants because their organs are so similar to humans. A hog heart at the time of slaughter, for example, is about the size of an adult human heart.
Other organs from pigs being researched for transplantation into humans include kidneys, liver and lungs.
According to Reuters prior efforts at pig-to-human transplants have failed because of genetic differences that caused organ rejection or viruses that posed an infection risk.
Scientists have tackled that problem by editing away potentially harmful genes.
In the heart implanted in Bennett, three genes previously linked with organ rejection were “knocked out” of the donor pig, and six human genes linked with immune acceptance were inserted into the pig genome.
Researchers also deleted a pig gene to prevent excessive growth of the pig heart tissue.
The work was funded in part with a $15.7 million research grant to evaluate Revivicor’s genetically-modified pig hearts in baboon studies.
In addition to the genetic changes to the pig heart, Bennett received an experimental anti-rejection drug made by Kiniksa Pharmaceuticals based in Lexington, Mass.
Health
Jalal Jalali discusses health cooperation with head of CDE in Kabul
Noor Jalal Jalali, Minister of Public Health, met Thursday with Anthony Dutemple, Director General of the Chain of Hope (CDE), to discuss numerous issues around health.
Jalali discussed the organization’s strategy, maternal and child health activities, support for emergency obstetric and gynecological services, provision of training programs aimed at enhancing the capacity of healthcare workers, equipping the cardiac treatment department of Indira Gandhi Hospital, and expanding coordination and cooperation in the health sector.
The Ministry of Public Health stated that Jalali described the cooperation of partner institutions and organizations as important for strengthening the health sector and called for further collaboration in expanding adult cardiac treatment services at Ibn Sina Chest Hospital, equipping and standardizing the cardiac treatment department at Indira Gandhi Hospital, and improving the capacity of healthcare workers.
During the meeting, representatives of the Chain of Hope emphasized their continued support for Afghanistan’s health sector and pledged the necessary cooperation in the aforementioned areas.
Health
Midwives Day: UN urges greater investment to protect mothers and newborns in Afghanistan
UNFPA added that improving access to skilled midwives is key to ensuring safer pregnancies and addressing persistent gaps in healthcare services for women and children.
Marking the International Day of the Midwife, the United Nations Population Fund in Afghanistan has called for urgent investment in midwifery services to help reduce maternal and newborn deaths across the country.
In a message shared on X, UNFPA said expanding the global midwifery workforce — including the addition of up to one million midwives — would be one of the most effective ways to save lives by improving access to antenatal care, safe deliveries, and postnatal support.
The agency stressed that midwives are central to strengthening healthcare systems and preventing avoidable deaths, particularly in Afghanistan where maternal and child health indicators remain among the most challenging.
UNFPA added that improving access to skilled midwives is key to ensuring safer pregnancies and addressing persistent gaps in healthcare services for women and children.
The organization reaffirmed its commitment to maternal and newborn health programmes and called on international partners to sustain support for strengthening Afghanistan’s healthcare workforce.
Health
Three dead in suspected hantavirus outbreak on cruise ship
Hantavirus is a rare but potentially serious infection transmitted primarily through contact with rats or mice or their droppings.
Three people have died following a suspected outbreak of hantavirus aboard a cruise vessel operated by Oceanwide Expeditions, as the ship remains stationed off the coast of Cape Verde island.
The vessel, which had been travelling from Argentina, has been halted near the archipelago for at least 24 hours, with no clearance granted for passengers to disembark, according to local reports and the operator.
Among the dead are a Dutch couple, aged 70 and 69, who fell ill during the voyage and were evacuated from the ship. A third Dutch national has also died, with their body still on board.
A 69-year-old British passenger—currently the only confirmed case of the virus—is being treated in intensive care at a hospital in Johannesburg, South Africa, after being medically evacuated. Two crew members on the ship have also fallen ill and are in urgent need of care.
Oceanwide Expeditions said it is working with health authorities to manage the situation, but emphasized that the vessel has not yet received authorization to dock in Cape Verde.
Hantavirus is a rare but potentially serious infection transmitted primarily through contact with rats or mice or their droppings. Symptoms can initially resemble flu but may rapidly progress to severe respiratory complications. There is no specific antiviral treatment, and care is typically supportive, with early medical intervention considered critical.
Health officials have not yet confirmed the source of the suspected outbreak, and investigations are ongoing as authorities monitor the condition of passengers and crew still aboard the ship.
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