Health
U.S. man recovering after ‘breakthrough’ pig-heart transplant
A U.S. man with terminal heart disease was implanted with a genetically modified pig heart in a first-of-its-kind surgery, and three days later the patient is doing well, his doctors reported on Monday.
The surgery, performed by a team at the University of Maryland Medicine, is among the first to demonstrate the feasibility of a pig-to-human heart transplant, a field made possible by new gene editing tools, Reuters reported.
If proven successful, scientists hope pig organs could help alleviate shortages of donor organs.
“This was a breakthrough surgery and brings us one step closer to solving the organ shortage crisis. There are simply not enough donor human hearts available to meet the long list of potential recipients,” Dr. Bartley Griffith, who surgically transplanted the pig heart into the patient, said in a statement.
“We are proceeding cautiously, but we are also optimistic that this first-in-the-world surgery will provide an important new option for patients in the future,” Griffith added.
According to the report for 57-year-old David Bennett of Maryland, the heart transplant was his last option.
“It was either die or do this transplant. I want to live. I know it’s a shot in the dark, but it’s my last choice,” Bennett said a day before his surgery, according to a statement released by the university.
To move ahead with the experimental surgery, the university obtained an emergency authorization from the U.S. Food and Drug Administration on New Year’s Eve through its compassionate use program.
“The FDA used our data and data on the experimental pig to authorize the transplant in an end-stage heart disease patient who had no other treatment options,” said Dr. Muhammad Mohiuddin, who heads the University’s program on xenotransplantation – transplanting animal organs into humans.
About 110,000 Americans are currently waiting for an organ transplant, and more than 6,000 patients die each year before getting one, according to organdonor.gov.
Bennett’s genetically modified pig heart was provided by Revivicor, a regenerative medicine company based in Blacksburg, Virginia. On the morning of the surgery, the transplant team removed the pig’s heart and placed it into a special device to preserve its function until the surgery, read the report.
Pigs have long been a tantalizing source of potential transplants because their organs are so similar to humans. A hog heart at the time of slaughter, for example, is about the size of an adult human heart.
Other organs from pigs being researched for transplantation into humans include kidneys, liver and lungs.
According to Reuters prior efforts at pig-to-human transplants have failed because of genetic differences that caused organ rejection or viruses that posed an infection risk.
Scientists have tackled that problem by editing away potentially harmful genes.
In the heart implanted in Bennett, three genes previously linked with organ rejection were “knocked out” of the donor pig, and six human genes linked with immune acceptance were inserted into the pig genome.
Researchers also deleted a pig gene to prevent excessive growth of the pig heart tissue.
The work was funded in part with a $15.7 million research grant to evaluate Revivicor’s genetically-modified pig hearts in baboon studies.
In addition to the genetic changes to the pig heart, Bennett received an experimental anti-rejection drug made by Kiniksa Pharmaceuticals based in Lexington, Mass.
Health
WHO warns aid cuts disrupting healthcare services across Afghanistan
Speaking to Ariana News, WHO Representative in Afghanistan said cuts in humanitarian assistance have placed the country’s health sector under increasing pressure.
The World Health Organization (WHO) has warned that declining international humanitarian funding is disrupting healthcare services across Afghanistan, forcing some health facilities to close and limiting access to essential medical care.
Speaking to Ariana News, WHO Representative in Afghanistan Edwin Ceniza Salvador said cuts in humanitarian assistance have placed the country’s health sector under increasing pressure, with many healthcare centers struggling to remain operational.
He said the funding shortfall is largely due to the growing number of humanitarian crises around the world, which have diverted international financial resources away from Afghanistan.
Salvador stressed that while continued humanitarian support remains essential, Afghanistan must also increase domestic investment in healthcare to build a more sustainable system.
“We have unfortunately seen a decline in global humanitarian funding in recent months because new emergencies have emerged in different parts of the world,” Salvador said. “As a result, many health facilities in Afghanistan are facing difficulties, and some have been forced to close. Alongside continued humanitarian support, greater domestic investment and increased funding for the health sector are essential.”
He noted that Afghanistan continues to face the effects of years of conflict, natural disasters and drought, making humanitarian assistance a critical lifeline for millions of people.
Despite the funding challenges, Salvador said the country has made progress in key health indicators, including increased childhood vaccination coverage and a decline in maternal mortality. However, he said expanding access to healthcare will require broader cooperation across government institutions and development partners.
The WHO warning comes amid growing concern from UN agencies over shrinking humanitarian funding for Afghanistan. Aid organizations have warned that reduced international assistance, coupled with the return of millions of Afghan migrants and the increasing impact of natural disasters, could further strain the country’s already fragile healthcare system and deepen the humanitarian crisis.
Health
Kabul opens cardiac hospital for children
A pediatric hospital for treating heart diseases, particularly congenital heart defects such as holes in the heart, has been inaugurated in Kabul by the Afghan Red Crescent Society.
Officials from the organization say the hospital has the capacity to treat up to 2,000 patients annually and will provide free diagnosis, treatment, and heart surgery services around the clock.
Shahabuddin Delawar, head of the Afghan Red Crescent Society, said the construction costs of the facility were covered through the organization’s own budget.
Previously, many patients suffering from heart conditions, especially children with holes in the heart, had to seek treatment at private hospitals or medical centers abroad due to limited access to specialized services inside the country.
Abdul Salam Hanafi, Administrative Deputy Prime Minister, said during the inauguration ceremony that the opening of the facility would help provide treatment for a large number of patients in need. He added that economic challenges had previously prevented many patients from accessing necessary medical services.
The head of the Afghan Red Crescent Society said local and foreign specialist doctors at the hospital will provide free, 24-hour cardiac services to patients, with efforts underway to ensure quality medical care.
Meanwhile, specialists at the hospital said modern medical equipment for diagnosing and treating heart diseases has been prepared at the facility.
The opening of the hospital offers new hope for patients, particularly children with congenital heart conditions, allowing them to receive free and specialized cardiac treatment inside Afghanistan and reducing the need for costly treatment abroad.
Health
OCHA warns Afghanistan’s maternal health system under mounting strain
The agency estimated that the country recorded 638 maternal deaths for every 100,000 live births in 2024 — the highest rate in Asia and the seventh highest globally.
The United Nations Office for the Coordination of Humanitarian Affairs (OCHA) has warned that Afghanistan’s maternal healthcare system is facing mounting pressure as humanitarian needs continue to grow, leaving millions of women and girls at risk of losing access to essential health services.
In its Afghanistan Humanitarian Update for June 2026, OCHA said more than 10.7 million women and girls are expected to require humanitarian assistance this year, making them among the populations most severely affected by the country’s prolonged humanitarian crisis.
The agency said ongoing restrictions affecting women’s movement, education and employment, coupled with economic hardship and declining humanitarian funding, have significantly reduced access to healthcare and other essential services while increasing protection risks and deepening vulnerabilities.
According to OCHA, Afghanistan continues to have one of the world’s highest maternal mortality rates. The agency estimated that the country recorded 638 maternal deaths for every 100,000 live births in 2024 — the highest rate in Asia and the seventh highest globally.
OCHA said the situation has been exacerbated by shortages of female healthcare workers, inadequate funding, limited supplies of essential medicines and gaps in emergency obstetric and neonatal care. These challenges are contributing to preventable deaths among mothers and newborns, particularly in rural and hard-to-reach communities where access to medical facilities remains limited.
The UN agency also warned of the long-term impact of restrictions on girls’ education, saying they threaten the future of Afghanistan’s healthcare workforce. Citing UNICEF estimates, OCHA said the country could lose more than 25,000 female teachers and health professionals by 2030 if current restrictions remain in place, potentially worsening shortages of female doctors, nurses and midwives.
During a recent assessment mission to Bamyan Province, OCHA highlighted the growing burden on local health facilities. Bamyan Provincial Hospital, the province’s main referral centre, continues to provide critical maternal and newborn services and houses the area’s only neonatal intensive care unit. However, the hospital is struggling to meet increasing demand with limited resources.
The agency said many expectant mothers arrive only after developing serious pregnancy-related complications because of long travel distances, poor road infrastructure and a lack of reliable referral services, reducing the chances of timely treatment.
OCHA called for sustained international support to strengthen Afghanistan’s fragile health system, warning that continued investment in maternal and newborn healthcare will be essential to reducing preventable deaths and ensuring that women, particularly those in remote areas, can access life-saving medical services.
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