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U.S. man recovering after ‘breakthrough’ pig-heart transplant

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A U.S. man with terminal heart disease was implanted with a genetically modified pig heart in a first-of-its-kind surgery, and three days later the patient is doing well, his doctors reported on Monday.

The surgery, performed by a team at the University of Maryland Medicine, is among the first to demonstrate the feasibility of a pig-to-human heart transplant, a field made possible by new gene editing tools, Reuters reported.

If proven successful, scientists hope pig organs could help alleviate shortages of donor organs.

“This was a breakthrough surgery and brings us one step closer to solving the organ shortage crisis. There are simply not enough donor human hearts available to meet the long list of potential recipients,” Dr. Bartley Griffith, who surgically transplanted the pig heart into the patient, said in a statement.

“We are proceeding cautiously, but we are also optimistic that this first-in-the-world surgery will provide an important new option for patients in the future,” Griffith added.

According to the report for 57-year-old David Bennett of Maryland, the heart transplant was his last option.

“It was either die or do this transplant. I want to live. I know it’s a shot in the dark, but it’s my last choice,” Bennett said a day before his surgery, according to a statement released by the university.

To move ahead with the experimental surgery, the university obtained an emergency authorization from the U.S. Food and Drug Administration on New Year’s Eve through its compassionate use program.

“The FDA used our data and data on the experimental pig to authorize the transplant in an end-stage heart disease patient who had no other treatment options,” said Dr. Muhammad Mohiuddin, who heads the University’s program on xenotransplantation – transplanting animal organs into humans.

About 110,000 Americans are currently waiting for an organ transplant, and more than 6,000 patients die each year before getting one, according to organdonor.gov.

Bennett’s genetically modified pig heart was provided by Revivicor, a regenerative medicine company based in Blacksburg, Virginia. On the morning of the surgery, the transplant team removed the pig’s heart and placed it into a special device to preserve its function until the surgery, read the report.

Pigs have long been a tantalizing source of potential transplants because their organs are so similar to humans. A hog heart at the time of slaughter, for example, is about the size of an adult human heart.

Other organs from pigs being researched for transplantation into humans include kidneys, liver and lungs.

According to Reuters prior efforts at pig-to-human transplants have failed because of genetic differences that caused organ rejection or viruses that posed an infection risk.

Scientists have tackled that problem by editing away potentially harmful genes.

In the heart implanted in Bennett, three genes previously linked with organ rejection were “knocked out” of the donor pig, and six human genes linked with immune acceptance were inserted into the pig genome.

Researchers also deleted a pig gene to prevent excessive growth of the pig heart tissue.

The work was funded in part with a $15.7 million research grant to evaluate Revivicor’s genetically-modified pig hearts in baboon studies.

In addition to the genetic changes to the pig heart, Bennett received an experimental anti-rejection drug made by Kiniksa Pharmaceuticals based in Lexington, Mass.

Health

Afghanistan, Uzbekistan move to expand cooperation in pharmaceutical sector

The two sides discussed expanding cooperation in the production and regulation of medicines and health products.

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Afghanistan’s Ministry of Public Health has announced that Abdul Basir Qane, Director General of Drug and Health Products Regulation at the ministry’s Food and Drug Deputy, held talks with Uzbek health officials during his visit to Uzbekistan to strengthen bilateral cooperation in the pharmaceutical sector.

According to a statement issued by the ministry, Qane and his technical delegation met with Abdullah Azizov, head of Uzbekistan’s regulatory authority for medical and pharmaceutical industries, along with other senior officials.

The two sides discussed expanding cooperation in the production and regulation of medicines and health products, facilitating the entry of Uzbek pharmaceutical manufacturers into the Afghan market, implementing inspections in line with Good Manufacturing Practice (GMP) standards, streamlining the registration process for medicines, and increasing bilateral trade in pharmaceutical products.

The discussions also covered the development of laboratory infrastructure, capacity building and training for specialists, the exchange of expertise in regulatory and inspection fields, and broader technical and professional cooperation between the two countries.

At the conclusion of the meeting, both sides reaffirmed their commitment to strengthening long-term cooperation in the pharmaceutical and health products sector, supporting the activities of pharmaceutical companies in both markets, and continuing dialogue on mutually beneficial joint projects, the ministry said.

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Health

Polio cases in Afghanistan rise to six in 2026 as two new cases confirmed

According to the WHO, one of the newly confirmed cases was identified in Nari district of Kunar province, while the other was reported in Nahr-e-Siraj district of Helmand province.

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The World Health Organization (WHO) has announced that the number of confirmed polio cases in Afghanistan has risen to six in 2026, following the detection of two new infections in the country.

According to the WHO, one of the newly confirmed cases was identified in Nari district of Kunar province, while the other was reported in Nahr-e-Siraj district of Helmand province. The organization also stated that 34 positive environmental samples of wild poliovirus have been recorded in Afghanistan so far this year.

The report adds that in 2025, a total of 52 wild poliovirus type 1 cases were confirmed across Afghanistan and Pakistan, including 21 cases in Afghanistan and 31 in Pakistan.

WHO further noted that in 2026 so far, nine wild poliovirus type 1 cases have been reported across both countries, with six in Afghanistan and three in Pakistan.

Health experts say that low public awareness, resistance from some families to vaccination campaigns, and limited access to remote areas remain key factors behind the continued spread of the disease.

They emphasize that polio is incurable and vaccination is the only effective way to prevent infection.

Public health specialists also stress the need to expand immunization coverage, particularly in hard-to-reach areas, and to strengthen public awareness campaigns, warning that eradication efforts will remain difficult without broad community cooperation.

Afghanistan and Pakistan remain the only two countries in the world where wild poliovirus is still endemic and has not been fully eradicated.

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Health

Health ministry urges greater public participation in blood donation

The appeal was made on Saturday as health officials marked World Blood Donor Day, an annual event aimed at raising awareness about the importance of voluntary blood donation and recognizing the contribution of donors in saving lives.

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Afghanistan’s Ministry of Public Health has called on citizens to increase their participation in blood donation campaigns, warning that many patients still struggle to obtain compatible blood in emergencies despite improvements in the country’s blood management system.

The appeal was made on Saturday as health officials marked World Blood Donor Day, an annual event aimed at raising awareness about the importance of voluntary blood donation and recognizing the contribution of donors in saving lives.

Speaking at the ceremony, officials highlighted the critical role blood donors play in supporting the healthcare system and ensuring that hospitals have adequate supplies for patients requiring urgent treatment.

Abdul Wali Haqqani, Deputy Minister for Health Services at the Ministry of Public Health, said that shortages in blood reserves continue to pose challenges for healthcare providers, particularly when patients require specific blood types.

“Unfortunately, patients who need blood do not always have immediate access to compatible negative blood groups,” Haqqani said. “Blood donation is a simple yet invaluable humanitarian act. The World Health Organization recommends that at least one percent of a country’s population donate blood regularly to maintain sufficient reserves.”

Haqqani stressed that increasing public participation in blood donation could significantly improve the availability of life-saving blood supplies and strengthen healthcare services across the country.

Meanwhile, Wahdat Alkozi, Director of Curative Medicine at the ministry, said Afghanistan has made notable progress in blood management in recent years. He noted that standardized blood separation and storage systems are now operating at the Central Blood Bank and several regional hospitals.

“We are working to expand these systems throughout the country so that patients can have greater access to safe and standardized blood services,” Alkozi said.

According to officials from the Central Blood Bank, more than 220,000 units of blood were collected from voluntary donors over the past year. The blood was used in the treatment of more than 250,000 patients nationwide, underscoring the growing demand for blood supplies in hospitals and healthcare facilities.

However, Niazgul Niazmand, head of the Central Blood Bank, said the shortage of negative blood groups remains a major challenge due to the limited number of donors with those blood types.

Health experts emphasize that blood donation not only helps save the lives of accident victims, surgical patients, mothers experiencing childbirth complications, and individuals suffering from serious illnesses, but can also benefit donors by promoting healthy blood circulation and stimulating the production of new blood cells.

World Blood Donor Day is observed every year on June 14 to encourage voluntary blood donation and raise awareness about the ongoing need for safe blood and blood products around the world.

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