Afghanistan’s Foreign Minister Amir Khan Muttaqi has strongly condemned a Pakistani airstrike on Kabul, saying it killed more than 408 people and wounded over 260, most of them patients at a drug rehabilitation centre.

Speaking to diplomats and representatives from various organizations in Kabul, Muttaqi said the late-night strike targeted one of the most vulnerable groups in society—people undergoing treatment for drug addiction with support from humanitarian organisations.

He described the attack as a serious violation of humanitarian and Islamic principles, accusing Pakistan of deliberately hitting civilian facilities.

He said the strike came despite ongoing mediation efforts by regional countries, including China, and followed earlier goodwill gestures by

Afghanistan, such as the release of Pakistani detainees during Ramadan.

According to Muttaqi, repeated attacks since February—including strikes on civilian areas in multiple provinces—have eroded trust in diplomatic solutions.

Muttaqi warned that Afghan forces would continue “proportionate and legitimate” defensive responses if attacks persist, stressing that Afghanistan does not seek conflict but will defend its sovereignty and territory.

He also urged the international community, particularly regional and Muslim countries, to condemn the strike, warning that continued escalation by Pakistan risks destabilising the wider region and undermining major economic and development initiatives.

The United Nations Assistance Mission in Afghanistan (UNAMA) said Tuesday that in Afghanistan, civilians are bearing the cost of the ongoing conflict between Kabul and Islamabad.

In a statement, UNAMA said that under international law, all parties to the conflict must respect and protect the sick and wounded, healthcare workers, hospitals, and ambulances.

The organization added that these laws prohibit any attacks on hospitals and ambulances.

According to UNAMA, between 24 February and before 16 March, it has recorded at least 74 civilian deaths and 212 others injured in Afghanistan as a result of the hostilities.

UNAMA once again called for de-escalation and a permanent ceasefire, urging Afghanistan and Pakistan to act in accordance with their obligations under international law and to protect civilians.

Following a Monday night attack by Pakistan’s military regime on the Omid Drug Rehabilitation Hospital in Kabul, at least 400 people were killed and around 250 others were injured.