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US, Hungarian scientists win Nobel Prize for research that led to Covid vaccines

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Scientists Katalin Kariko of Hungary and Drew Weissman of the United States respectively won the 2023 Nobel Prize in Physiology or Medicine for discoveries enabling the development of mRNA Covid-19 vaccines, the award-giving body has announced.

“The 2023 Nobel Prize in Physiology or Medicine has been awarded to Katalin Kariko and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against Covid-19,” the body said on Monday

The prize, among the most prestigious in the scientific world, is selected by the Nobel Assembly of Sweden’s Karolinska Institute Medical University and also comes with 11 million Swedish crowns (about $1 million).

Kariko was senior vice president and head of RNA protein replacement at BioNTech until 2022 and has since acted as an adviser to the company. She is also a professor at the University of Szeged in Hungary and adjunct professor at the University of Pennsylvania’s Perelman School of Medicine.

Weissman is professor in vaccine research at the Perelman School.

Kariko found a way to prevent the immune system from launching an inflammatory reaction against lab-made mRNA, previously seen as a major hurdle against any therapeutic use of mRNA.

Together with Weissman, she showed in 2005 that adjustments to nucleosides, the molecular letters that write the mRNA’s genetic code, can keep the mRNA under the immune system’s radar.

‘Major impact on society’

“So this year’s Nobel Prize recognises their basic science discovery that fundamentally changed our understanding of how mRNA interacts with the immune system and had a major impact on society during the recent pandemic,” said Rickard Sandberg, member of the Nobel Assembly at Karolinska Institute

The medicine prize kicks off this year’s awards with the remaining five to be unveiled in the coming days.

The prizes, first handed out in 1901, were created by Swedish dynamite inventor and wealthy businessman Alfred Nobel, and are awarded for achievements in science, literature and peace, and in later years also for economics.

The Swedish king will present the prizes at a ceremony in Stockholm on Dec. 10, the anniversary of Nobel’s death, followed by a lavish banquet at city hall.

Last year’s medicine prize went to Swede Svante Paabo for sequencing the genome of the Neanderthal, an extinct relative of present-day humans, and for discovering a previously unknown human relative, the Denisovans.

Other past winners include Alexander Fleming, who shared the 1945 prize for the discovery of penicillin, and Karl Landsteiner in 1930 for his discovery of human blood groups.

Health

Jalal Jalali discusses health cooperation with head of CDE in Kabul

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Noor Jalal Jalali, Minister of Public Health, met Thursday with Anthony Dutemple, Director General of the Chain of Hope (CDE), to discuss numerous issues around health.

Jalali discussed the organization’s strategy, maternal and child health activities, support for emergency obstetric and gynecological services, provision of training programs aimed at enhancing the capacity of healthcare workers, equipping the cardiac treatment department of Indira Gandhi Hospital, and expanding coordination and cooperation in the health sector.

The Ministry of Public Health stated that Jalali described the cooperation of partner institutions and organizations as important for strengthening the health sector and called for further collaboration in expanding adult cardiac treatment services at Ibn Sina Chest Hospital, equipping and standardizing the cardiac treatment department at Indira Gandhi Hospital, and improving the capacity of healthcare workers.

During the meeting, representatives of the Chain of Hope emphasized their continued support for Afghanistan’s health sector and pledged the necessary cooperation in the aforementioned areas.

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Health

Midwives Day: UN urges greater investment to protect mothers and newborns in Afghanistan

UNFPA added that improving access to skilled midwives is key to ensuring safer pregnancies and addressing persistent gaps in healthcare services for women and children.

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Marking the International Day of the Midwife, the United Nations Population Fund in Afghanistan has called for urgent investment in midwifery services to help reduce maternal and newborn deaths across the country.

In a message shared on X, UNFPA said expanding the global midwifery workforce — including the addition of up to one million midwives — would be one of the most effective ways to save lives by improving access to antenatal care, safe deliveries, and postnatal support.

The agency stressed that midwives are central to strengthening healthcare systems and preventing avoidable deaths, particularly in Afghanistan where maternal and child health indicators remain among the most challenging.

UNFPA added that improving access to skilled midwives is key to ensuring safer pregnancies and addressing persistent gaps in healthcare services for women and children.

The organization reaffirmed its commitment to maternal and newborn health programmes and called on international partners to sustain support for strengthening Afghanistan’s healthcare workforce.

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Health

Three dead in suspected hantavirus outbreak on cruise ship

Hantavirus is a rare but potentially serious infection transmitted primarily through contact with rats or mice or their droppings.

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Three people have died following a suspected outbreak of hantavirus aboard a cruise vessel operated by Oceanwide Expeditions, as the ship remains stationed off the coast of Cape Verde island.

The vessel, which had been travelling from Argentina, has been halted near the archipelago for at least 24 hours, with no clearance granted for passengers to disembark, according to local reports and the operator.

Among the dead are a Dutch couple, aged 70 and 69, who fell ill during the voyage and were evacuated from the ship. A third Dutch national has also died, with their body still on board.

A 69-year-old British passenger—currently the only confirmed case of the virus—is being treated in intensive care at a hospital in Johannesburg, South Africa, after being medically evacuated. Two crew members on the ship have also fallen ill and are in urgent need of care.

Oceanwide Expeditions said it is working with health authorities to manage the situation, but emphasized that the vessel has not yet received authorization to dock in Cape Verde.

Hantavirus is a rare but potentially serious infection transmitted primarily through contact with rats or mice or their droppings. Symptoms can initially resemble flu but may rapidly progress to severe respiratory complications. There is no specific antiviral treatment, and care is typically supportive, with early medical intervention considered critical.

Health officials have not yet confirmed the source of the suspected outbreak, and investigations are ongoing as authorities monitor the condition of passengers and crew still aboard the ship.

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