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US, Hungarian scientists win Nobel Prize for research that led to Covid vaccines

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(Last Updated On: October 2, 2023)

Scientists Katalin Kariko of Hungary and Drew Weissman of the United States respectively won the 2023 Nobel Prize in Physiology or Medicine for discoveries enabling the development of mRNA Covid-19 vaccines, the award-giving body has announced.

“The 2023 Nobel Prize in Physiology or Medicine has been awarded to Katalin Kariko and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against Covid-19,” the body said on Monday

The prize, among the most prestigious in the scientific world, is selected by the Nobel Assembly of Sweden’s Karolinska Institute Medical University and also comes with 11 million Swedish crowns (about $1 million).

Kariko was senior vice president and head of RNA protein replacement at BioNTech until 2022 and has since acted as an adviser to the company. She is also a professor at the University of Szeged in Hungary and adjunct professor at the University of Pennsylvania’s Perelman School of Medicine.

Weissman is professor in vaccine research at the Perelman School.

Kariko found a way to prevent the immune system from launching an inflammatory reaction against lab-made mRNA, previously seen as a major hurdle against any therapeutic use of mRNA.

Together with Weissman, she showed in 2005 that adjustments to nucleosides, the molecular letters that write the mRNA’s genetic code, can keep the mRNA under the immune system’s radar.

‘Major impact on society’

“So this year’s Nobel Prize recognises their basic science discovery that fundamentally changed our understanding of how mRNA interacts with the immune system and had a major impact on society during the recent pandemic,” said Rickard Sandberg, member of the Nobel Assembly at Karolinska Institute

The medicine prize kicks off this year’s awards with the remaining five to be unveiled in the coming days.

The prizes, first handed out in 1901, were created by Swedish dynamite inventor and wealthy businessman Alfred Nobel, and are awarded for achievements in science, literature and peace, and in later years also for economics.

The Swedish king will present the prizes at a ceremony in Stockholm on Dec. 10, the anniversary of Nobel’s death, followed by a lavish banquet at city hall.

Last year’s medicine prize went to Swede Svante Paabo for sequencing the genome of the Neanderthal, an extinct relative of present-day humans, and for discovering a previously unknown human relative, the Denisovans.

Other past winners include Alexander Fleming, who shared the 1945 prize for the discovery of penicillin, and Karl Landsteiner in 1930 for his discovery of human blood groups.

Health

Nationwide polio vaccination campaign kicks off across Afghanistan

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(Last Updated On: April 29, 2024)

Afghanistan launched a polio vaccination campaign on Monday aimed at protecting around 10.72 million children under the age of 5, the Health Ministry announced.

The four-day campaign will cover 31 of the country’s 34 provinces.

Vaccinations in Ghor, Daikundi and Bamiyan provinces will be implemented later due to recent rains and cold weather, the ministry said in a statement.

“Together with our partners, we are committed to eradicating polio from Afghanistan,” said Dr Qalandar Ebad, the acting minister of public health.

“We will work tirelessly and continue polio vaccination campaigns and complementary health services until we reach the goal of fully eradicating polio.”

The ministry urged religious scholars and local elders to cooperate with vaccine providers to fight polio, a debilitating disease that can lead to paralysis and death.

In December, the World Health Organization (WHO) warned that the repatriation of migrants from neighboring Pakistan has increased the risk of spreading the virus. Since then, Afghanistan has conducted at least three rounds of nationwide vaccinations.

Vaccination campaigns in Afghanistan and Pakistan often face challenges due to conspiracy theories that polio vaccines cause infertility or that vaccinators are spies.

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Azerbaijan urged to help improve capacity of Afghan health workers

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(Last Updated On: April 22, 2024)

Acting Minister of Public Health Qalandar Ebad, in a meeting with Azerbaijan’s ambassador, Ilham Mohammadov, called for the country’s assistance in improving the capacity of Afghanistan’s health workers.

The two sides also discussed cooperation in the health sector, capacity building of Afghan health workers, and Azerbaijan’s role in the health sector and other issues, according to a statement released by the Public Health Ministry.

Azerbaijan’s envoy said that his country seeks to cooperate with Afghanistan in a sustainable manner in the field of health.

In other news, the foundation stone for the construction of oxygen production facility was laid at the Indira Gandhi children hospital in Kabul.

Officials of the Ministry of Public Health said that the facility will be built with the financial and technical assistance of the World Health Organization, and with the capacity to produce 200 cylinders of oxygen daily to meet not only the needs of the hospital, but also other health facilities.

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Health

Balkh health officials report sharp increase in number of cancer patients

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(Last Updated On: April 18, 2024)

Balkh Public Health Department officials say there has been a significant increase in the number of patients with cancer in the province.

“In 1401, about 2,613 OPD (out patient department) cases were registered with us. In 1402, these figures were 4,912 cases,” said Ehsanullah Kaliwal, the head of the oncology department at Balkh Regional Hospital.

Some doctors say genetic factors, environmental pollution, arbitrary use of medicines, and excessive consumption of meat were reasons for the sharp increase.

One doctor said cancer was also hereditry.

However, a large percentage of cancer patients in Balkh have stomach cancer. Many of them have appealed for the government to improve treatment facilities.

According to health officials, in the first month of this solar year (April), 423 cancer patients visited this hospital for treatment.

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