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Russia launches rescue ship to space station after leaks

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Russia launched a rescue ship on Friday for two cosmonauts and a NASA astronaut whose original ride home sprang a dangerous leak while parked at the International Space Station.

The new, empty Soyuz capsule should arrive at the orbiting lab on Sunday, The Associated Press reported.

The capsule leak in December was blamed on a micrometeorite that punctured an external radiator, draining it of coolant. The same thing appeared to happen again earlier this month, this time on a docked Russian cargo ship. Camera views showed a small hole in each spacecraft.

The Russian Space Agency delayed the launch of the replacement Soyuz, looking for any manufacturing defects. No issues were found, and the agency proceeded with Friday’s predawn launch from Kazakhstan of the capsule with bundles of supplies strapped into the three seats.

Given the urgent need for this capsule, two top NASA officials traveled from the U.S. to observe the launch in person. To everyone’s relief, the capsule safely reached orbit nine minutes after liftoff — “a perfect ride to orbit,” NASA Mission Control’s Rob Navias reported from Houston.

Officials had determined it was too risky to bring NASA’s Frank Rubio and Russia’s Sergey Prokopyev and Dmitri Petelin back in their damaged Soyuz next month as originally planned. With no coolant, the cabin temperature would spike during the trip back to Earth, potentially damaging computers and other equipment, and exposing the suited-up crew to excessive heat.

Until the new Soyuz pulls up, emergency plans call for Rubio to switch to a SpaceX crew capsule that’s docked at the space station. Prokopyev and Petelin remain assigned to their damaged Soyuz in the unlikely need for a fast getaway. Having one less person on board would keep the temperature down to a hopefully manageable level, Russian engineers concluded.

The damaged Soyuz will return to Earth with no one aboard by the end of March, so engineers can examine it.

The three men launched in this Soyuz last September on what should have been a six-month mission. They’ll now stay in space for a full year, until a new capsule is ready for their crew replacements for liftoff in September. It was their Soyuz that just launched with no one on board.

“The Russians are continuing to take a really close look” at both spacecraft leaks, NASA’s deputy space station program manager Dana Weigel told reporters earlier this week. “They’re looking at everything … to try to understand that.”

NASA has a fresh crew of four launching atop a SpaceX rocket early Monday morning from Florida’s Kennedy Space Center. SpaceX’s William Gerstenmaier said the four astronauts returning to Earth in a few weeks already have inspected the Dragon capsule that will carry them home and “it all checked out fine.”

Science & Technology

UAE sets minimum social media age at 15, mandates age checks

The government said the measures were designed ​to address concerns ​over children’s exposure ⁠to inappropriate content, unsafe online interactions, excessive social media use and the collection of personal data.

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The United Arab Emirates has set a minimum age of 15 for social media use, becoming the first Arab ​country to introduce such a restriction as governments worldwide seek to ‌address growing concerns over the impact of online platforms on children.

Under a resolution approved on Thursday, children under 15 will be prohibited from creating, using or operating ​personal social media accounts. The ban means they will not ​be able to post content, comment, share or join public ⁠groups, the government’s media office said, Reuters reported.

Teenagers aged 15 and 16 will ​be allowed to use social media platforms subject to enhanced safeguards, including ​age-appropriate content controls, restrictions on interaction with unknown users, screen-time management tools and parental supervision features.

The rules apply to all social media platforms operating in the UAE and ​require companies to implement robust age-verification measures, including digital identity checks ​and artificial intelligence-supported technologies. Self-declaration of age will not be accepted as a valid ‌form ⁠of verification.

Platforms must also disable accounts created by children under 15, prevent users from circumventing age-verification systems and refrain from using children’s personal data for targeted advertising or behavioural profiling.

The government said the measures were designed ​to address concerns ​over children’s exposure ⁠to inappropriate content, unsafe online interactions, excessive social media use and the collection of personal data.

Social media companies ​will have up to 12 months to comply with ​the ⁠new regulations.

The UAE said the framework aligns with international efforts to strengthen online child protection while balancing digital access with safety.

Several countries, including Australia and ⁠others ​in Europe, have moved to tighten restrictions on ​children’s use of social media amid mounting concerns about its effects on mental health and ​online safety.

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Iran banks hit by major cyber attack

Officials said a technical investigation confirmed that the disruptions were the result of a cyberattack.

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Several major Iranian banks experienced service disruptions on Saturday following a cyberattack, according to the Coordinating Committee of Iran’s state-owned banks.

The outage affected four major financial institutions, including Bank Melli Iran, Bank Saderat Iran, and Bank Tejarat, causing interruptions to mobile and online banking services, automated teller machines (ATMs), point-of-sale (POS) terminals, and some card transactions.

Officials said a technical investigation confirmed that the disruptions were the result of a cyberattack.

The affected banks stated that their technical teams immediately implemented precautionary measures after detecting the incident in an effort to safeguard customer information and protect banking infrastructure.

Qatasi, secretary of the Coordinating Committee of Iran’s state-owned banks, said necessary recovery and repair measures had been carried out.

Authorities said there is currently no evidence that customer data was accessed without authorization, and no data breach has been reported.

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Science & Technology

GLP-1 drugs may have a beneficial effect across many types of cancer

The drugs, originally designed to treat diabetes and found to promote weight loss, have also shown benefits for heart risks, sleep apnea and alcohol and substance abuse.

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A growing body of evidence suggests that popular GLP-1 drugs, widely used for weight loss and diabetes, can provide protection against many types of cancer, Reuters reported.

More than two dozen studies presented over the past few days at the American Society of Clinical Oncology meeting in Chicago found that patients taking the drugs showed lower risks of developing cancer and disease progression, better survival, and ​improved responses to some treatments, compared with people who were not taking the GLP-1s.

The studies included analyses of clinical records and real-world databases tracking patients taking Novo Nordisk’s (NOVOb.CO), Wegovy ‌or Ozempic, Eli Lilly’s (LLY.N), Zepbound or Mounjaro, or older GLP-1 treatments.

The studies were not designed to show how or why GLP-1 use might affect cancer treatment. But researchers believe by reducing inflammation, regulating insulin signaling and possibly engaging directly with tumor biology, they may contribute to a protective effect in cancer patients.

“Chronic inflammation is a fundamental biological pathway involved in the development and progression of many cancers,” said Dr. Elizabeth Susan McDonald of the University of Pennsylvania.

McDonald on Tuesday reported ​on a study of 110,000 women, showing those who took GLP-1 medications were up to 35% less likely to develop breast cancer than those who did not.

While obesity itself is a ​known risk factor for certain cancers, the anti-inflammatory effects of GLP-1s will likely prove to have a role in cancer prevention, McDonald said.

GLP-1 drugs include semaglutide, the active ingredient in Wegovy, Ozempic and Rybelsus; tirzepatide, sold as Mounjaro and Zepbound, as well as Lilly’s Trulicity, or dulaglutide, and Novo’s older liraglutide, sold as ​Saxenda and Victoza.

Some of the strongest signals of benefit came from a study of more than 12,000 patients that showed GLP-1 use was associated with markedly lower odds of cancers advancing to metastatic disease, particularly ​in lung, breast, colorectal and liver cancers.

People with those cancers who took liraglutide, pramlintide, dulaglutide, tirzepatide, lixisenatide, or semaglutide were 38% to 50% less likely to see the disease spread than people who took drugs from a different class of diabetes medicines known as gliptins.

Reduced cancer incidence, longer survival, and fewer metastases were also seen with GLP-1 use in patients with endometrial, bladder and prostate cancers, as well as in those with small intestine neoplasms and blood cancers, multiple studies ​found.

A separate analysis of patients treated at U.S. community oncology practices found GLP-1 use was associated with significantly better overall survival across six tumor types – breast, prostate, colorectal, lung, liver and kidney – with a ​roughly one-third reduction in the risk of death.

Researchers also reported that cancer patients receiving immunotherapies such as Merck’s (MRK.N), Keytruda and Bristol Myers Squibb’s (BMY.N), Opdivo or Yervoy appeared to fare better when they were taking GLP-1 drugs, suggesting a ‌possible interaction ⁠with the immune system.

GLP-1 users with type 2 diabetes and stage 3 kidney disease had substantially lower mortality and lower rates of several malignancies, particularly lung, colorectal, and hepatocellular cancers, than non-users, read the report.

While GLP-1 medications carry a warning regarding a possible association with a type of thyroid cancer based on rodent studies, researchers say the recent findings point to a potential beneficial class effect across tumor types, rather than benefits confined to a small subset of cancers.

The drugs, originally designed to treat diabetes and found to promote weight loss, have also shown benefits for heart risks, sleep apnea and alcohol and substance abuse.

“These drugs have never been just glucose-lowering agents,” ​Dr. Marcin Chwistek of the Fox Chase Cancer ​Center in Philadelphia said at an ASCO press ⁠briefing.

Researchers cautioned that nearly all of the data presented were from observational studies, raising the risk of confounding factors. Patients prescribed GLP-1 drugs may differ in important ways, including overall health, access to care and concurrent treatments, that could influence outcomes.

While the various studies tried to account for those differences, none ​can prove the drugs improve cancer outcomes. Experts said trials in which GLP-1s are added to standard treatment in some cancer patients but not ​others are needed to establish ⁠clear anti-cancer benefits. Some trials are already being planned.

The apparent cancer benefits were not clearly tied to the drugs’ weight-loss effects, suggesting that alone does not explain the findings, Reuters reported.

A seven-year study with nearly 120,000 participants found GLP-1s were associated with lower rates of new prostate cancer diagnoses in high-risk men, compared to drugs such as Merck’s Propecia and GSK’s (GSK.L), Avodart, which are used to shrink enlarged prostate glands.

GLP-1 users had a “very small” reduction in ⁠body weight at ​one year, said Dr. Colton Jones of the University of Texas San Antonio Mays Cancer Center who presented the study ​at ASCO.

“We hypothesize that both weight loss and a direct anti-cancer effect and anti-inflammatory effect may be driving the associations observed in our study,” Jones said.

ASCO expert Chwistek said anti-inflammatory and immune-modulating properties have long suggested broader effects of GLP-1s.

Referring to one of ​the largest studies, Chwistek said: “What’s new here is the consistency across tumor types, and data this large and this consistent warrant a prospective randomized trial.”

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