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North Korea launches second hypersonic missile in fiery test

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North Korea fired a “hypersonic missile” this week that successfully hit a target, state news agency KCNA reported on Thursday, its second such test as the country pursues new military capabilities amid stalled denuclearisation talks, Reuters reported.

The launch on Wednesday was the first by North Korea since October and was detected by several militaries in the region, drawing criticism from governments in the United States, South Korea, and Japan.

According to the report North Korea first tested a hypersonic missile in September, joining a race headed by major military powers to deploy the advanced weapons system.

Hypersonic weapons usually fly towards targets at lower altitudes than ballistic missiles and can achieve more than five times the speed of sound – or about 6,200 km per hour (3,850 mph).

Despite their name, analysts say the main feature of hypersonic weapons is not speed – which can sometimes be matched or exceeded by traditional ballistic missile warheads – but their manoeuvrability.

In Wednesday’s test, the “hypersonic gliding warhead” detached from its rocket booster and manoeuvred 120 km (75 miles) laterally before it “precisely hit” a target 700 km (430 miles) away, KCNA reported.

The missile demonstrated its ability to combine “multi-step glide jump flight and strong lateral manoeuvring,” KCNA said.

The test also confirmed components such as flight control and its ability to operate in the winter, KCNA added.

“The successive successes in the test launches in the hypersonic missile sector have strategic significance in that they hasten a task for modernizing strategic armed force of the state,” the KCNA report said.

While it has not tested nuclear bombs or long-range intercontinental ballistic missiles (ICBMs) since 2017, in recent years North Korea has developed and launched a range of more manoeuvrable missiles and warheads likely aimed at being able to overcome missile defences like those wielded by South Korea and the United States, analysts have said.

“My impression is that the North Koreans have identified hypersonic gliders as a potentially useful qualitative means to cope with missile defence,” said Ankit Panda, a senior fellow at the U.S.-based Carnegie Endowment for International Peace.

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Hypersonic weapons are considered the next generation of arms that aim to rob adversaries of reaction time and traditional defeat mechanisms, read the report.

Last month the United States completed construction of a massive, $1.5 billion long-range radar for a homeland missile defence system in Alaska that it says can track ballistic missiles as well as hypersonic weapons from countries such as North Korea, Reuters reported.

Photos of the missile used in Wednesday’s test show what analysts said is a liquid-fueled ballistic missile with a conical-shaped Manoeuvrable Reentry Vehicle (MaRV) blasting off from a wheeled launch vehicle in a cloud of flame and smoke.

It is a different version than the weapon tested last year, and was first unveiled at a defence exhibition in Pyongyang in October, Panda said.

“They likely set up at least two separate development programmes,” he added. “One of these was the Hwasong-8, which was tested in September. This missile, which shares a few features in common with the Hwasong-8, is another.”

In a call with Japanese Foreign Minister Yoshimasa Hayashi on Thursday, U.S. Secretary of State Antony Blinken condemned the North Korea missile launch and discussed cooperation to achieve complete denuclearization and lasting peace on the Korean Peninsula, the U.S. State Department said in a statement.

“We take any new capability seriously, and as we’ve said, we condemn (North Korea’s) continued testing of ballistic missiles, which are destabilizing to the region and to the international community,” a State Department spokesperson said later.

According to Reuters talks aimed at persuading North Korea to surrender its nuclear weapons and ballistic missile arsenal have been stalled since a series of summits between leader Kim Jong Un and then-U.S. President Donald Trump broke down with no agreement.

U.S. President Joe Biden’s administration has said it is open to talking to North Korea, but Pyongyang has said American overtures are empty rhetoric without more substantive changes to “hostile policies” such as military drills and sanctions, read the report.

The latest test came just hours before South Korean President Moon Jae-in attended a groundbreaking ceremony for a rail line he hopes will eventually connect the divided Korean peninsula, casting doubts over his hopes for an eleventh-hour diplomatic breakthrough with North Korea before his five-year term ends in May.

Science & Technology

UAE sets minimum social media age at 15, mandates age checks

The government said the measures were designed ​to address concerns ​over children’s exposure ⁠to inappropriate content, unsafe online interactions, excessive social media use and the collection of personal data.

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The United Arab Emirates has set a minimum age of 15 for social media use, becoming the first Arab ​country to introduce such a restriction as governments worldwide seek to ‌address growing concerns over the impact of online platforms on children.

Under a resolution approved on Thursday, children under 15 will be prohibited from creating, using or operating ​personal social media accounts. The ban means they will not ​be able to post content, comment, share or join public ⁠groups, the government’s media office said, Reuters reported.

Teenagers aged 15 and 16 will ​be allowed to use social media platforms subject to enhanced safeguards, including ​age-appropriate content controls, restrictions on interaction with unknown users, screen-time management tools and parental supervision features.

The rules apply to all social media platforms operating in the UAE and ​require companies to implement robust age-verification measures, including digital identity checks ​and artificial intelligence-supported technologies. Self-declaration of age will not be accepted as a valid ‌form ⁠of verification.

Platforms must also disable accounts created by children under 15, prevent users from circumventing age-verification systems and refrain from using children’s personal data for targeted advertising or behavioural profiling.

The government said the measures were designed ​to address concerns ​over children’s exposure ⁠to inappropriate content, unsafe online interactions, excessive social media use and the collection of personal data.

Social media companies ​will have up to 12 months to comply with ​the ⁠new regulations.

The UAE said the framework aligns with international efforts to strengthen online child protection while balancing digital access with safety.

Several countries, including Australia and ⁠others ​in Europe, have moved to tighten restrictions on ​children’s use of social media amid mounting concerns about its effects on mental health and ​online safety.

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Iran banks hit by major cyber attack

Officials said a technical investigation confirmed that the disruptions were the result of a cyberattack.

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Several major Iranian banks experienced service disruptions on Saturday following a cyberattack, according to the Coordinating Committee of Iran’s state-owned banks.

The outage affected four major financial institutions, including Bank Melli Iran, Bank Saderat Iran, and Bank Tejarat, causing interruptions to mobile and online banking services, automated teller machines (ATMs), point-of-sale (POS) terminals, and some card transactions.

Officials said a technical investigation confirmed that the disruptions were the result of a cyberattack.

The affected banks stated that their technical teams immediately implemented precautionary measures after detecting the incident in an effort to safeguard customer information and protect banking infrastructure.

Qatasi, secretary of the Coordinating Committee of Iran’s state-owned banks, said necessary recovery and repair measures had been carried out.

Authorities said there is currently no evidence that customer data was accessed without authorization, and no data breach has been reported.

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Science & Technology

GLP-1 drugs may have a beneficial effect across many types of cancer

The drugs, originally designed to treat diabetes and found to promote weight loss, have also shown benefits for heart risks, sleep apnea and alcohol and substance abuse.

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A growing body of evidence suggests that popular GLP-1 drugs, widely used for weight loss and diabetes, can provide protection against many types of cancer, Reuters reported.

More than two dozen studies presented over the past few days at the American Society of Clinical Oncology meeting in Chicago found that patients taking the drugs showed lower risks of developing cancer and disease progression, better survival, and ​improved responses to some treatments, compared with people who were not taking the GLP-1s.

The studies included analyses of clinical records and real-world databases tracking patients taking Novo Nordisk’s (NOVOb.CO), Wegovy ‌or Ozempic, Eli Lilly’s (LLY.N), Zepbound or Mounjaro, or older GLP-1 treatments.

The studies were not designed to show how or why GLP-1 use might affect cancer treatment. But researchers believe by reducing inflammation, regulating insulin signaling and possibly engaging directly with tumor biology, they may contribute to a protective effect in cancer patients.

“Chronic inflammation is a fundamental biological pathway involved in the development and progression of many cancers,” said Dr. Elizabeth Susan McDonald of the University of Pennsylvania.

McDonald on Tuesday reported ​on a study of 110,000 women, showing those who took GLP-1 medications were up to 35% less likely to develop breast cancer than those who did not.

While obesity itself is a ​known risk factor for certain cancers, the anti-inflammatory effects of GLP-1s will likely prove to have a role in cancer prevention, McDonald said.

GLP-1 drugs include semaglutide, the active ingredient in Wegovy, Ozempic and Rybelsus; tirzepatide, sold as Mounjaro and Zepbound, as well as Lilly’s Trulicity, or dulaglutide, and Novo’s older liraglutide, sold as ​Saxenda and Victoza.

Some of the strongest signals of benefit came from a study of more than 12,000 patients that showed GLP-1 use was associated with markedly lower odds of cancers advancing to metastatic disease, particularly ​in lung, breast, colorectal and liver cancers.

People with those cancers who took liraglutide, pramlintide, dulaglutide, tirzepatide, lixisenatide, or semaglutide were 38% to 50% less likely to see the disease spread than people who took drugs from a different class of diabetes medicines known as gliptins.

Reduced cancer incidence, longer survival, and fewer metastases were also seen with GLP-1 use in patients with endometrial, bladder and prostate cancers, as well as in those with small intestine neoplasms and blood cancers, multiple studies ​found.

A separate analysis of patients treated at U.S. community oncology practices found GLP-1 use was associated with significantly better overall survival across six tumor types – breast, prostate, colorectal, lung, liver and kidney – with a ​roughly one-third reduction in the risk of death.

Researchers also reported that cancer patients receiving immunotherapies such as Merck’s (MRK.N), Keytruda and Bristol Myers Squibb’s (BMY.N), Opdivo or Yervoy appeared to fare better when they were taking GLP-1 drugs, suggesting a ‌possible interaction ⁠with the immune system.

GLP-1 users with type 2 diabetes and stage 3 kidney disease had substantially lower mortality and lower rates of several malignancies, particularly lung, colorectal, and hepatocellular cancers, than non-users, read the report.

While GLP-1 medications carry a warning regarding a possible association with a type of thyroid cancer based on rodent studies, researchers say the recent findings point to a potential beneficial class effect across tumor types, rather than benefits confined to a small subset of cancers.

The drugs, originally designed to treat diabetes and found to promote weight loss, have also shown benefits for heart risks, sleep apnea and alcohol and substance abuse.

“These drugs have never been just glucose-lowering agents,” ​Dr. Marcin Chwistek of the Fox Chase Cancer ​Center in Philadelphia said at an ASCO press ⁠briefing.

Researchers cautioned that nearly all of the data presented were from observational studies, raising the risk of confounding factors. Patients prescribed GLP-1 drugs may differ in important ways, including overall health, access to care and concurrent treatments, that could influence outcomes.

While the various studies tried to account for those differences, none ​can prove the drugs improve cancer outcomes. Experts said trials in which GLP-1s are added to standard treatment in some cancer patients but not ​others are needed to establish ⁠clear anti-cancer benefits. Some trials are already being planned.

The apparent cancer benefits were not clearly tied to the drugs’ weight-loss effects, suggesting that alone does not explain the findings, Reuters reported.

A seven-year study with nearly 120,000 participants found GLP-1s were associated with lower rates of new prostate cancer diagnoses in high-risk men, compared to drugs such as Merck’s Propecia and GSK’s (GSK.L), Avodart, which are used to shrink enlarged prostate glands.

GLP-1 users had a “very small” reduction in ⁠body weight at ​one year, said Dr. Colton Jones of the University of Texas San Antonio Mays Cancer Center who presented the study ​at ASCO.

“We hypothesize that both weight loss and a direct anti-cancer effect and anti-inflammatory effect may be driving the associations observed in our study,” Jones said.

ASCO expert Chwistek said anti-inflammatory and immune-modulating properties have long suggested broader effects of GLP-1s.

Referring to one of ​the largest studies, Chwistek said: “What’s new here is the consistency across tumor types, and data this large and this consistent warrant a prospective randomized trial.”

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