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US surgeons successfully test pig kidney transplant in human patient

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(Last Updated On: October 20, 2021)

For the first time, a pig kidney has been transplanted into a human without triggering immediate rejection by the recipient’s immune system, a potentially major advance that could eventually help alleviate a dire shortage of human organs for transplant.

The procedure done at NYU Langone Health in New York City involved use of a pig whose genes had been altered so that its tissues no longer contained a molecule known to trigger almost immediate rejection.

The recipient was a brain-dead patient with signs of kidney dysfunction whose family consented to the experiment before she was due to be taken off of life support, researchers told Reuters.

For three days, the new kidney was attached to her blood vessels and maintained outside her body, giving researchers access to it.

Test results of the transplanted kidney’s function “looked pretty normal,” said transplant surgeon Dr. Robert Montgomery, who led the study.

The kidney made “the amount of urine that you would expect” from a transplanted human kidney, he said, and there was no evidence of the vigorous, early rejection seen when unmodified pig kidneys are transplanted into non-human primates.

The recipient’s abnormal creatinine level – an indicator of poor kidney function – returned to normal after the transplant, Montgomery said.

In the United States, nearly 107,000 people are presently waiting for organ transplants, including more than 90,000 awaiting a kidney, according to the United Network for Organ Sharing. Wait times for a kidney average three-to-five years.

Researchers have been working for decades on the possibility of using animal organs for transplants, but have been stymied over how to prevent immediate rejection by the human body.

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Nationwide polio vaccination campaign kicks off across Afghanistan

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(Last Updated On: April 29, 2024)

Afghanistan launched a polio vaccination campaign on Monday aimed at protecting around 10.72 million children under the age of 5, the Health Ministry announced.

The four-day campaign will cover 31 of the country’s 34 provinces.

Vaccinations in Ghor, Daikundi and Bamiyan provinces will be implemented later due to recent rains and cold weather, the ministry said in a statement.

“Together with our partners, we are committed to eradicating polio from Afghanistan,” said Dr Qalandar Ebad, the acting minister of public health.

“We will work tirelessly and continue polio vaccination campaigns and complementary health services until we reach the goal of fully eradicating polio.”

The ministry urged religious scholars and local elders to cooperate with vaccine providers to fight polio, a debilitating disease that can lead to paralysis and death.

In December, the World Health Organization (WHO) warned that the repatriation of migrants from neighboring Pakistan has increased the risk of spreading the virus. Since then, Afghanistan has conducted at least three rounds of nationwide vaccinations.

Vaccination campaigns in Afghanistan and Pakistan often face challenges due to conspiracy theories that polio vaccines cause infertility or that vaccinators are spies.

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Azerbaijan urged to help improve capacity of Afghan health workers

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(Last Updated On: April 22, 2024)

Acting Minister of Public Health Qalandar Ebad, in a meeting with Azerbaijan’s ambassador, Ilham Mohammadov, called for the country’s assistance in improving the capacity of Afghanistan’s health workers.

The two sides also discussed cooperation in the health sector, capacity building of Afghan health workers, and Azerbaijan’s role in the health sector and other issues, according to a statement released by the Public Health Ministry.

Azerbaijan’s envoy said that his country seeks to cooperate with Afghanistan in a sustainable manner in the field of health.

In other news, the foundation stone for the construction of oxygen production facility was laid at the Indira Gandhi children hospital in Kabul.

Officials of the Ministry of Public Health said that the facility will be built with the financial and technical assistance of the World Health Organization, and with the capacity to produce 200 cylinders of oxygen daily to meet not only the needs of the hospital, but also other health facilities.

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Balkh health officials report sharp increase in number of cancer patients

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(Last Updated On: April 18, 2024)

Balkh Public Health Department officials say there has been a significant increase in the number of patients with cancer in the province.

“In 1401, about 2,613 OPD (out patient department) cases were registered with us. In 1402, these figures were 4,912 cases,” said Ehsanullah Kaliwal, the head of the oncology department at Balkh Regional Hospital.

Some doctors say genetic factors, environmental pollution, arbitrary use of medicines, and excessive consumption of meat were reasons for the sharp increase.

One doctor said cancer was also hereditry.

However, a large percentage of cancer patients in Balkh have stomach cancer. Many of them have appealed for the government to improve treatment facilities.

According to health officials, in the first month of this solar year (April), 423 cancer patients visited this hospital for treatment.

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