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US and Britain roll out campaigns after poliovirus detected in water samples

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The detection of poliovirus in wastewater samples from New York and London has sparked fears of a possible public health crisis but health experts in the United States believe that the virus is unlikely to secure widespread transmission in the country, especially in highly vaccinated areas.

Medical Daily reported that the US declared the eradication of poliovirus in September 1994, and not many people are aware of the disease it causes and its symptoms at present. There is also limited awareness on how it spreads.

According to the Centers for Disease Control and Prevention (CDC), poliovirus spreads through person-to-person contact and other ways, such as the oral-fecal route and droplets.

Poliovirus is so contagious it can contaminate food and water in unsanitary conditions. Transmission is inevitable when a person makes contact with the feces from an infected person while infection via droplets from a sneeze or cough is less common, Medical Daily reported.

The CDC noted that an infected person could spread the virus almost immediately before and up to two weeks after the symptoms of the disease appear. Once the virus enters the mouth, it can stay in the intestines for many weeks. Asymptomatic people can still pass the virus to other people and make them sick, the report read.

Last month, the US reported its first case of polio in almost a decade.

Meanwhile, Britain rolled out urgent polio vaccinations this week for all London-based children below 10 after the discovery of polio traces in sewage samples across several London boroughs. The move was made after the detection of polio in wastewater samples from New York, London and even Israel sparked fears of a wider outbreak.

Among the symptoms of polio, paralysis is the one most commonly associated with the disease since it can lead to permanent disability or even death. Scientific data showed between 2 and 10 out of 200 infected people develop paralysis and die because the virus can significantly impact the muscles used for breathing.

Since there is no cure or specific treatment for paralytic polio, patients rely on long-term physical or occupational therapy to help them with arm or leg weakness.

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Four-day polio vaccination campaign begins across Afghanistan

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A nationwide polio vaccination campaign got underway across Afghanistan on Monday.

The four-day campaign aims to vaccinate around 12.77 million children under the age of five against polio.

Officials said the campaign is aimed at strengthening protection for children against polio and preventing the spread of the virus.

However, in the southern zone of the country, the polio vaccination campaign will begin one day later, on Tuesday, to ensure better implementation.

According to the information provided, Afghanistan has conducted one nationwide and two sub-national polio vaccination campaigns so far this year. The current campaign is the fourth of the year. In addition, localized campaigns and public awareness programs have also been carried out.

Officials said some environmental samples linked to the polio virus have tested positive. However, the Ministry of Public Health has not so far confirmed any human cases of polio.

According to officials, investigations into suspected cases are ongoing, and information on confirmed human cases will be shared once the assessments are completed and sufficient evidence is available.

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Afghanistan faces cancer treatment crisis

Spokesperson for the Ministry of Public Health, said dozens of cancer treatment centers are operating across the country.

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The Afghanistan Cancer Foundation has raised concern over the rising number of cancer cases across the country, saying at least 1.5 million people are currently suffering from the disease.

According to figures released on Saturday, September 11, about 50,000 new cases are recorded annually. The figures are based on data from the Ministry of Public Health and international organizations.

Shafiq Shinwari, head of the Afghan Cancer Foundation, said in a recent interview that breast and uterine cancers are among the most common cancers in women, while lung, stomach, prostate and colon cancers are widespread among men.

He said cancer is the second-leading cause of death in Afghanistan after heart disease.

Cancer specialist Dr. Rahim Gul Darwish identified smoking and tobacco use, poor hygiene and unhealthy diets as major factors contributing to the spread of the disease.

Meanwhile, Sharafat Zaman Amarkhail, spokesperson for the Ministry of Public Health, said dozens of cancer treatment centers are operating across the country. However, he acknowledged serious shortages of modern equipment and facilities needed to provide comprehensive treatment.

The situation has been further aggravated by the departure of hundreds of medical specialists and healthcare workers since the Islamic Emirate returned to power, according to reports.

Afghan patients have also faced growing difficulties accessing treatment abroad. Many previously travelled to Pakistan for cancer care, but border closures and restrictions on Pakistani visas have made access more difficult.

Doctors say cancer patients require continuous treatment and regular specialist care, warning that shortages of facilities and restrictions on cross-border travel are increasing the risks for patients.

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Genetically modified pig kidney keeps man alive for record nine months

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A genetically modified pig kidney has kept a 66-year-old man with end-stage kidney disease alive without dialysis for a record nine months, marking the first time a pig kidney has successfully served as a temporary “bridge” to a human kidney transplant.

Tim Andrews, from New Hampshire, was suffering from severe kidney failure caused by type 2 diabetes. Doctors said he had only a 9% chance of receiving a human kidney within five years, while facing a more than 40% risk of dying or being removed from the transplant waiting list.

Tim Andrews preparing for surgery in January 2025

Surgeons at Mass General Brigham in Massachusetts transplanted a kidney from a genetically modified Yucatan miniature pig named Wilma into Andrews in January 2025. The kidney functioned for 271 days, allowing him to remain free of dialysis before it began to fail.

After the pig kidney was removed, Andrews spent several months back on dialysis before receiving a kidney from a deceased human donor. The human kidney was functioning well after six months of follow-up, according to findings published in the medical journal The Lancet.

The transplant represents the longest dialysis-free survival recorded following a pig kidney xenotransplant in a living person. It is also the first documented case in which a patient successfully moved from a pig kidney transplant to a human kidney transplant.

Before the procedure, Wilma’s genome underwent 69 genetic modifications. Some changes were intended to reduce the risk of viruses being transmitted to humans, while others were designed to make the pig kidney more compatible with the human immune system and reduce the risk of rejection.

Andrews described the procedure as a “miracle”, saying it allowed him to return to everyday activities. He said he was able to cook, vacuum and take long walks with his dog.

The development could offer a potential solution to the severe shortage of human organs available for transplantation. Kidney transplantation provides the best survival prospects and quality of life for patients with end-stage kidney disease, but the global demand for donor kidneys far exceeds the supply.

Dr Leonardo Riella of Mass General Brigham said the shortage of organs remains “the greatest crisis” in transplantation. He said genetically modified animal organs could initially be used to help patients avoid dialysis while they wait for a human donor kidney and could eventually become a long-term treatment option if their safety and durability are established.

The pig kidney began showing damage to its blood vessels after about six months, eventually leading to organ failure and its removal nine months after transplantation.

Doctors found no new antibodies against human tissue following the procedure, suggesting the pig kidney did not make Andrews’ subsequent human transplant more difficult. No pig viruses or other pig pathogens were detected at any point.

The researchers cautioned that the result is based on a single patient with no comparison group. They said the outcome also depended on careful patient selection and intensive specialist care that may not be available in all settings.

Further clinical trials will be needed to determine whether genetically modified pig kidneys can safely and reliably be used as a bridge for other patients facing long waits for human organs.

The researchers said the case nevertheless provides new evidence that pig kidney transplantation could help address the global organ shortage and potentially offer patients a way to remain off dialysis while waiting for a human kidney.

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