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Chinese researchers find bat virus enters human cells via same pathway as COVID

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A newly discovered bat coronavirus uses the same cell-surface protein to gain entry into human cells as the SARS-CoV-2 virus that causes COVID-19, raising the possibility that it could someday spread to humans, Chinese researchers have reported.

The virus does not enter human cells as readily as SARS-CoV-2 does, the Chinese researchers reported in the journal Cell, opens new tab, noting some of its limitations, Reuters reported.

The scientists said that like SARS-CoV-2, the bat virus HKU5-CoV-2 contains a feature known as the furin cleavage site that helps it to enter cells via the ACE2 receptor protein on cell surfaces.

In lab experiments, HKU5-CoV-2 infected human cells with high ACE2 levels in test tubes and in models of human intestines and airways.

In further experiments, the researchers identified monoclonal antibodies and antiviral drugs that target the bat virus.

Bloomberg, which reported on the study earlier on Friday, said the paper identifying the bat virus had moved shares of COVID vaccine makers. Pfizer shares closed up 1.5% on Friday, Moderna climbed 5.3% and Novavax was up about 1% on a down day for the broader market.

Asked about concerns raised by the report of another pandemic resulting from this new virus, Dr. Michael Osterholm, an infectious disease expert at the University of Minnesota, called the reaction to the study “overblown.”

He said there is a lot of immunity in the population to similar SARS viruses compared with 2019, which may reduce the pandemic risk.

The study itself noted that the virus has significantly less binding affinity to human ACE2 than SARS-CoV-2, and other suboptimal factors for human adaptation suggest the “risk of emergence in human populations should not be exaggerated.”

 

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Afghanistan seeks India’s support in standardizing traditional medicine

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Afghanistan’s Minister of Public Health, Noor Jalal Jalali, has called for India’s cooperation in the standardization and development of traditional medicine during a meeting with India’s Minister for Ayurveda, Yoga & Naturopathy, Unani, Siddha and Homeopathy (AYUSH), Prataprao Jadhav.

The meeting focused on establishing a traditional medicine institute and a research center in Kabul, cooperation in training qualified professionals, and the signing of a bilateral memorandum of understanding. Minister Jalali stressed that standardizing traditional medicine is a pressing priority for Afghanistan and noted that India’s extensive expertise in this field would be highly beneficial.

For his part, the AYUSH minister reaffirmed India’s commitment to supporting Afghanistan by assisting in the establishment of a research center and institute in Kabul, developing and implementing academic curricula, and expanding cooperation across various areas related to traditional medicine.

 
 
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Health ministry holds meeting with envoys of international organizations in Kabul

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Noor Jalal Jalali, Minister of Public Health of Afghanistan, held a meeting in Kabul with representatives of the World Health Organization, UNICEF, the World Bank, the Asian Development Bank, the European Union, the UK Foreign, Commonwealth and Development Office (FCDO), and other international organizations.

According to the ministry’s statement, representatives of these international organizations discussed the delivery of health and development services, improving the management of aid and resources in the health sector, integrating health facilities and aligning them with the new policy, providing health services in accordance with the Ministry of Public Health’s policy, strengthening the immunization and vaccination sector, delivering services based on priorities, and ensuring sustained coordination.

During the meeting, Jalali stressed the need for transparency and attention to the ministry’s priorities in order to enhance the effectiveness and impact of health services. He added that the delivery of health services must be carried out in line with the ministry’s policy and through better management of existing international assistance.

Referring to vaccination campaigns, he stated that the recent measles and polio vaccination campaign had been implemented very successfully, and emphasized that necessary preparations should be made for upcoming campaigns.

He also provided information regarding the review of the BPHS and EPHS health packages and the establishment of a standardized system through technical committees.

In this meeting, Edwin Ceniza, the WHO Representative for Afghanistan, reaffirmed the organization’s continued cooperation with the Ministry of Public Health and expressed appreciation to the ministry’s leadership for their tireless efforts to improve the health system.

Representatives of these organizations pledged to maintain effective and sustained coordination and to provide their services within the country in accordance with the policies and principles of the Ministry of Public Health.

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IEA health delegation travels to Turkey

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Abdul Wali Haqqani, Deputy Minister for Health Services at the Ministry of Public Health of the Islamic Emirate of Afghanistan (IEA), has departed for Turkey on an official visit accompanied by a high-ranking delegation.

According to a statement released by the Health Ministry on Wednesday, the trip aims to acquire new health-sector expertise, assess Turkish medical and scientific institutions, meet with Turkish health and government officials, and strengthen bilateral cooperation.

During the visit, the delegation is scheduled to meet representatives from both public and private health sectors to support improvements in Afghanistan’s healthcare system and enhance coordination between the two countries, the statement added.

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