Health
Indian maker of syrup linked to death of children in Uzbekistan halts production
India’s drug regulator said on Thursday that it had inspected Marion Biotech’s production facility and promised more action based on the probe report after the company’s cough syrup was linked to the death of 19 children in Uzbekistan.
A legal representative of Marion Biotech said the Indian maker of pharmaceuticals and cosmetics regretted the deaths and the company has halted production of the Dok-1 Max syrup, Reuters reported.
The drug regulator reviewed the company’s Noida facility in the Uttar Pradesh state and is in regular touch with its Uzbekistan counterpart, the Indian health ministry said in a statement.
“The samples of the cough syrup have been taken from the manufacturing premises and sent to Regional Drugs Testing Laboratory, Chandigarh for testing,” the ministry said.
Uzbekistan’s health ministry said on Wednesday that at least 18 children in Samarkand city died after consuming the syrup manufactured by the Indian drugmaker.
Another child, a one-year-old, died after being given the syrup for five days, Uzbek news website report.uz said on Thursday, citing the Qashqadaryo regional prosecutor’s office.
Officials in the Samarkand region had initially not reported the deaths to the ministry, the report added, citing Health Minister Bekhzod Musayevand.
Seven employees were dismissed by the Uzbek ministry following a probe into the matter, and “disciplinary measures” were taken against some specialists. The Doc-1 Max tablets and syrups have also been withdrawn from all pharmacies, the Uzbek ministry added in its statement on Wednesday.
The syrup contained a toxic substance, ethylene glycol, and was administered in doses higher than the standard dose for children either by their parents, who mistook it for an anti-cold remedy, or on the advice of pharmacists, the Uzbekistan ministry said.
India’s Ministry of Chemicals and Fertilizers issued an order on Thursday, laying out specifications to regulate the sale of ethylene glycol from the end of March.
The incident follows another similar one in Gambia, where deaths of at least 70 children had been linked to cough and cold syrups manufactured by New Delhi-based Maiden Pharmaceuticals Ltd. The Indian government and also the company, however, have since denied the allegations.
India is known as the ‘pharmacy of the world,’ and has doubled its pharmaceutical exports over the last decade, touching $24.5 billion in the last fiscal year.
Health
UNICEF issues emergency tender to secure mpox vaccines
Depending on the production capacity of manufacturers, agreements for up to 12 million doses through 2025 can be made, according to the statement.
The United Nations Children's Fund (UNICEF) has issued an emergency tender to secure mpox vaccines for crisis-hit countries in collaboration with the Gavi vaccine alliance, Africa CDC and the World Health Organization, the organizations said in a joint statement on Saturday.
Depending on the production capacity of manufacturers, agreements for up to 12 million doses through 2025 can be made, according to the statement.
Under the tender, UNICEF will set up conditional supply agreements with vaccine manufacturers, the statement said.
This will enable UNICEF to purchase and ship vaccines without delay, once financing, demand, readiness and regulatory requirements are confirmed, Reuters reported.
The collaboration - which would also include working with the Vaccine Alliance and the Pan American Health Organization as well as with Gavi, the Africa Centers for Disease Control and Prevention and WHO - would facilitate donations of vaccines from existing stockpiles in high-income countries.
The statement added that WHO is reviewing information submitted by manufacturers on Aug. 23, and expects to complete a review for an emergency use listing by mid-September.
The agency is reviewing applications for emergency licences for two vaccines made by Bavarian Nordic (BAVA.CO), opens new tab and Japan's KM Biologics, read the report.
Earlier in August, the WHO declared mpox a global public health emergency following an outbreak of the viral infection in the Democratic Republic of Congo that spread to neighbouring countries.
More than 18,000 suspected cases of mpox have been reported in Congo so far this year with 629 deaths, while over 150 cases have been confirmed in Burundi, WHO Director-General Tedros Adhanom Ghebreyesus said.
Sweden and Thailand have confirmed cases of the clade Ib type of the virus, outside of the Democratic Republic of Congo and neighboring countries.
Health
Ministry of Health says no reports in Afghanistan of monkey pox
So far, cases of monkeypox have been recorded in Pakistan, Sweden and Africa.
The Ministry of Public Health has announced that no suspected or positive cases of monkey pox have been registered in Afghanistan.
After receiving reports about two suspected cases of monkey pox in Kabul and Paktia, officials say that no suspected or positive cases of this disease have been registered in Afghanistan.
Sharaf Zaman Amarkhel, the spokesperson of the Ministry of Health, said on Tuesday that the ministry will announce it if there is a suspected or positive case of monkeypox.
Earlier, a number of media, citing health sources, reported that two suspected cases of monkey pox were detected in Kabul and Paktia.
The officials of the Ministry of Public Health announced nearly a week ago that they are trying to prevent the spread of the disease.
So far, cases of monkeypox have been recorded in Pakistan, Sweden and Africa.
The World Health Organization recently declared the outbreak of monkey pox a health emergency and said that the new strain of this virus is spreading.
Health
IEA forms technical committee to combat mpox threat
The Deputy Minister of Public Health appointed the teams to work together on the preparation of the list of duties and the definition of mpox, and present it for approval in the next week’s meeting.
The Ministry of Public Health on Thursday announced that the technical committee to fight and prevent mpox virus met under the leadership of deputy minister for health services, Abdul Wali Haqqani.
Directors of the Ministry of Public Health, and representatives of World Health Organization (WHO), the UN agency for children UNICEF, and the International Organization for Migration (IOM) were also present at the meeting.
According to the Ministry of Public Health's statement, the participants of the meeting discussed and exchanged views on the preparation of the list of duties for the technical team, the definition of mpox, and the necessary measures to prevent the virus in the country.
The Deputy Minister of Public Health appointed the teams to work together on the preparation of the list of duties and the definition of mpox, and present it for approval in the next week’s meeting.
The World Health Organization (WHO) has already declared a global health emergency in response to the widening mpox outbreak. The virus, which can be fatal in some cases, is known to spread through close contact and is particularly concerning given its potential to escalate into a pandemic.
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