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New injection could ‘revolutionize’ treatment of high blood pressure

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Drug trials are currently underway in the UK in what some experts have said is a huge breakthrough in treating high blood pressure. Just one injection every six months could lower high blood pressure, trial results suggest.

The new drug, zilebesiran, developed by US-based company Alnylam, is given as an injection rather than in traditional pill form.

High blood pressure, or hypertension, rarely has noticeable symptoms. But if untreated, it increases your risk of serious problems such as heart attacks and strokes.

Persistent high blood pressure can increase your risk of a number of serious and potentially life-threatening conditions, such as:

heart disease
heart attacks
strokes
heart failure
peripheral arterial disease
aortic aneurysms
kidney disease
vascular dementia

The Daily Mail reported that for the drug trials, 107 patients with hypertension were recruited to take part – 80 received a single injection of zilebesiran under the skin, while 32 received a placebo containing no active ingredients.

Five patients who initially received the placebo were later moved to zilebesiran.

Analysis revealed patients who received zilebesiran experienced a substantial reduction in systolic blood pressure – the force with which the heart pushes blood out and round the body – which lasted up to six months.

On average, systolic blood pressure lowered by over 10mmHg at a 200mg dose or more of the drug, and more than 20mmHg at the highest dose of 800mg.

A drop of this size can take someone with high blood pressure to within a much safer range.

Blood pressure naturally goes up and down throughout the course of the day, making it difficult to treat.

But the study found that the drop in blood pressure seen in patients who were treated with zilebesiran was consistent over 24 hours.

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Jalal Jalali discusses health cooperation with head of CDE in Kabul

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Noor Jalal Jalali, Minister of Public Health, met Thursday with Anthony Dutemple, Director General of the Chain of Hope (CDE), to discuss numerous issues around health.

Jalali discussed the organization’s strategy, maternal and child health activities, support for emergency obstetric and gynecological services, provision of training programs aimed at enhancing the capacity of healthcare workers, equipping the cardiac treatment department of Indira Gandhi Hospital, and expanding coordination and cooperation in the health sector.

The Ministry of Public Health stated that Jalali described the cooperation of partner institutions and organizations as important for strengthening the health sector and called for further collaboration in expanding adult cardiac treatment services at Ibn Sina Chest Hospital, equipping and standardizing the cardiac treatment department at Indira Gandhi Hospital, and improving the capacity of healthcare workers.

During the meeting, representatives of the Chain of Hope emphasized their continued support for Afghanistan’s health sector and pledged the necessary cooperation in the aforementioned areas.

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Midwives Day: UN urges greater investment to protect mothers and newborns in Afghanistan

UNFPA added that improving access to skilled midwives is key to ensuring safer pregnancies and addressing persistent gaps in healthcare services for women and children.

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Marking the International Day of the Midwife, the United Nations Population Fund in Afghanistan has called for urgent investment in midwifery services to help reduce maternal and newborn deaths across the country.

In a message shared on X, UNFPA said expanding the global midwifery workforce — including the addition of up to one million midwives — would be one of the most effective ways to save lives by improving access to antenatal care, safe deliveries, and postnatal support.

The agency stressed that midwives are central to strengthening healthcare systems and preventing avoidable deaths, particularly in Afghanistan where maternal and child health indicators remain among the most challenging.

UNFPA added that improving access to skilled midwives is key to ensuring safer pregnancies and addressing persistent gaps in healthcare services for women and children.

The organization reaffirmed its commitment to maternal and newborn health programmes and called on international partners to sustain support for strengthening Afghanistan’s healthcare workforce.

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Three dead in suspected hantavirus outbreak on cruise ship

Hantavirus is a rare but potentially serious infection transmitted primarily through contact with rats or mice or their droppings.

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Three people have died following a suspected outbreak of hantavirus aboard a cruise vessel operated by Oceanwide Expeditions, as the ship remains stationed off the coast of Cape Verde island.

The vessel, which had been travelling from Argentina, has been halted near the archipelago for at least 24 hours, with no clearance granted for passengers to disembark, according to local reports and the operator.

Among the dead are a Dutch couple, aged 70 and 69, who fell ill during the voyage and were evacuated from the ship. A third Dutch national has also died, with their body still on board.

A 69-year-old British passenger—currently the only confirmed case of the virus—is being treated in intensive care at a hospital in Johannesburg, South Africa, after being medically evacuated. Two crew members on the ship have also fallen ill and are in urgent need of care.

Oceanwide Expeditions said it is working with health authorities to manage the situation, but emphasized that the vessel has not yet received authorization to dock in Cape Verde.

Hantavirus is a rare but potentially serious infection transmitted primarily through contact with rats or mice or their droppings. Symptoms can initially resemble flu but may rapidly progress to severe respiratory complications. There is no specific antiviral treatment, and care is typically supportive, with early medical intervention considered critical.

Health officials have not yet confirmed the source of the suspected outbreak, and investigations are ongoing as authorities monitor the condition of passengers and crew still aboard the ship.

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