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US, Hungarian scientists win Nobel Prize for research that led to Covid vaccines

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Scientists Katalin Kariko of Hungary and Drew Weissman of the United States respectively won the 2023 Nobel Prize in Physiology or Medicine for discoveries enabling the development of mRNA Covid-19 vaccines, the award-giving body has announced.

“The 2023 Nobel Prize in Physiology or Medicine has been awarded to Katalin Kariko and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against Covid-19,” the body said on Monday

The prize, among the most prestigious in the scientific world, is selected by the Nobel Assembly of Sweden’s Karolinska Institute Medical University and also comes with 11 million Swedish crowns (about $1 million).

Kariko was senior vice president and head of RNA protein replacement at BioNTech until 2022 and has since acted as an adviser to the company. She is also a professor at the University of Szeged in Hungary and adjunct professor at the University of Pennsylvania’s Perelman School of Medicine.

Weissman is professor in vaccine research at the Perelman School.

Kariko found a way to prevent the immune system from launching an inflammatory reaction against lab-made mRNA, previously seen as a major hurdle against any therapeutic use of mRNA.

Together with Weissman, she showed in 2005 that adjustments to nucleosides, the molecular letters that write the mRNA’s genetic code, can keep the mRNA under the immune system’s radar.

‘Major impact on society’

“So this year’s Nobel Prize recognises their basic science discovery that fundamentally changed our understanding of how mRNA interacts with the immune system and had a major impact on society during the recent pandemic,” said Rickard Sandberg, member of the Nobel Assembly at Karolinska Institute

The medicine prize kicks off this year’s awards with the remaining five to be unveiled in the coming days.

The prizes, first handed out in 1901, were created by Swedish dynamite inventor and wealthy businessman Alfred Nobel, and are awarded for achievements in science, literature and peace, and in later years also for economics.

The Swedish king will present the prizes at a ceremony in Stockholm on Dec. 10, the anniversary of Nobel’s death, followed by a lavish banquet at city hall.

Last year’s medicine prize went to Swede Svante Paabo for sequencing the genome of the Neanderthal, an extinct relative of present-day humans, and for discovering a previously unknown human relative, the Denisovans.

Other past winners include Alexander Fleming, who shared the 1945 prize for the discovery of penicillin, and Karl Landsteiner in 1930 for his discovery of human blood groups.

Health

Afghan health minister, WHO hold talks on health services expansion

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Afghanistan’s Minister of Public Health, Noor Jalal Jalali, met with the head of the World Health Organization in Afghanistan, Edwin Ceniza Salvador, to discuss expanding healthcare services and strengthening coordination in the country.

According to a statement issued Tuesday by the Ministry of Public Health, the meeting was attended by officials from the WHO and other representatives and focused on key health sector priorities and areas of mutual cooperation.

Participants discussed the expansion of health services across Afghanistan, capacity-building initiatives for healthcare workers, and the development of cancer-related services. They also reviewed operational coordination, transparency in the delivery of health services, and preparations for upcoming health-related meetings.

During the meeting, Jalali emphasized the importance of aligning health projects and services with the ministry’s national policies and strategic documents.

He stressed that all health initiatives should be implemented based on the priorities and needs identified by the Ministry of Public Health.

The minister also urged WHO officials to enhance transparency and strengthen coordination with the ministry while taking practical steps to improve the quality of health services and ensure broader public access to healthcare across the country.

For his part, Salvador reaffirmed the WHO’s commitment to maintaining close cooperation with the Afghan health ministry and to delivering essential health services in accordance with the ministry’s policies and priorities.

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Afghanistan faces acute shortage of specialist doctors, officials urge ethics and expansion of health services

Noor Jalal Jalali, the Minister of Public Health, said the ministry is making sustained and intensive efforts to address the gap and expand access to healthcare services in remote and underserved areas of the country.

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Afghanistan is continuing to face a serious shortage of specialist doctors, health officials said during the graduation ceremony of specialist physicians from the General Directorate of Medical Specialization for the year 1404.

Noor Jalal Jalali, the Minister of Public Health, said the ministry is making sustained and intensive efforts to address the gap and expand access to healthcare services in remote and underserved areas of the country.

According to Jalali, hospitals are still absent across 318 districts nationwide. He added that initial construction work for hospitals has been completed in 100 of these areas, stressing that strengthening health infrastructure and training qualified specialists remain top priorities for the ministry.

Jalali also called on doctors and health officials to uphold their professional and religious responsibilities by treating patients with compassion, dignity, and good conduct. He emphasized that medical practice should not be driven by material gain, but by the pursuit of public service and the well-being of the people.

Speaking at the same ceremony, Hamdullah Nomani, Minister of Communications and Information Technology noted a decline in public trust toward some medical professionals, saying that despite the presence of many committed and ethical doctors, the behavior of a few motivated solely by financial gain has undermined patient confidence. He urged newly graduated specialists to serve with sincerity and restore public trust in Afghanistan’s healthcare system.

Meanwhile, Abdul Wali Sadiqi, the financial and administrative deputy minister of public health, advised graduates to remain committed to their profession, fulfill their responsibilities honestly, and serve the public with dedication. He stressed that efforts in national service should match those made in personal affairs.

In addition, Abdul Baqi Haqqani, head of the National Examinations Authority, highlighted that humans carry two fundamental responsibilities: worship of Allah and preservation of health, underscoring the vital role doctors play in safeguarding public health.

Health sector experts say Afghanistan now needs skilled and professional medical personnel more than ever, calling for increased investment in specialist training and healthcare infrastructure to meet the country’s growing needs.

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Afghan delegation heads to Turkey for medicine talks

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Naemullah Ayoubi, Director General of Drug and Health Products Regulation at Afghanistan’s Ministry of Public Health, has departed for Turkey on an official visit accompanied by a technical delegation.

The Ministry of Public Health said the delegation will hold meetings with officials from Turkey’s pharmaceutical regulatory authority and discuss a number of key issues related to the regulation of medicines and health products.

The delegation is also scheduled to visit several pharmaceutical manufacturing factories in Turkey.

According to the ministry, the visit aims to strengthen coordination between the two countries in the production and import of medicines, in order to ensure the availability of high-quality and affordable pharmaceuticals for people in Afghanistan in both the short and long term.

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