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New injection could ‘revolutionize’ treatment of high blood pressure

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Drug trials are currently underway in the UK in what some experts have said is a huge breakthrough in treating high blood pressure. Just one injection every six months could lower high blood pressure, trial results suggest.

The new drug, zilebesiran, developed by US-based company Alnylam, is given as an injection rather than in traditional pill form.

High blood pressure, or hypertension, rarely has noticeable symptoms. But if untreated, it increases your risk of serious problems such as heart attacks and strokes.

Persistent high blood pressure can increase your risk of a number of serious and potentially life-threatening conditions, such as:

heart disease
heart attacks
strokes
heart failure
peripheral arterial disease
aortic aneurysms
kidney disease
vascular dementia

The Daily Mail reported that for the drug trials, 107 patients with hypertension were recruited to take part – 80 received a single injection of zilebesiran under the skin, while 32 received a placebo containing no active ingredients.

Five patients who initially received the placebo were later moved to zilebesiran.

Analysis revealed patients who received zilebesiran experienced a substantial reduction in systolic blood pressure – the force with which the heart pushes blood out and round the body – which lasted up to six months.

On average, systolic blood pressure lowered by over 10mmHg at a 200mg dose or more of the drug, and more than 20mmHg at the highest dose of 800mg.

A drop of this size can take someone with high blood pressure to within a much safer range.

Blood pressure naturally goes up and down throughout the course of the day, making it difficult to treat.

But the study found that the drop in blood pressure seen in patients who were treated with zilebesiran was consistent over 24 hours.

Health

Afghan health minister, WHO hold talks on health services expansion

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Afghanistan’s Minister of Public Health, Noor Jalal Jalali, met with the head of the World Health Organization in Afghanistan, Edwin Ceniza Salvador, to discuss expanding healthcare services and strengthening coordination in the country.

According to a statement issued Tuesday by the Ministry of Public Health, the meeting was attended by officials from the WHO and other representatives and focused on key health sector priorities and areas of mutual cooperation.

Participants discussed the expansion of health services across Afghanistan, capacity-building initiatives for healthcare workers, and the development of cancer-related services. They also reviewed operational coordination, transparency in the delivery of health services, and preparations for upcoming health-related meetings.

During the meeting, Jalali emphasized the importance of aligning health projects and services with the ministry’s national policies and strategic documents.

He stressed that all health initiatives should be implemented based on the priorities and needs identified by the Ministry of Public Health.

The minister also urged WHO officials to enhance transparency and strengthen coordination with the ministry while taking practical steps to improve the quality of health services and ensure broader public access to healthcare across the country.

For his part, Salvador reaffirmed the WHO’s commitment to maintaining close cooperation with the Afghan health ministry and to delivering essential health services in accordance with the ministry’s policies and priorities.

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Afghanistan faces acute shortage of specialist doctors, officials urge ethics and expansion of health services

Noor Jalal Jalali, the Minister of Public Health, said the ministry is making sustained and intensive efforts to address the gap and expand access to healthcare services in remote and underserved areas of the country.

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Afghanistan is continuing to face a serious shortage of specialist doctors, health officials said during the graduation ceremony of specialist physicians from the General Directorate of Medical Specialization for the year 1404.

Noor Jalal Jalali, the Minister of Public Health, said the ministry is making sustained and intensive efforts to address the gap and expand access to healthcare services in remote and underserved areas of the country.

According to Jalali, hospitals are still absent across 318 districts nationwide. He added that initial construction work for hospitals has been completed in 100 of these areas, stressing that strengthening health infrastructure and training qualified specialists remain top priorities for the ministry.

Jalali also called on doctors and health officials to uphold their professional and religious responsibilities by treating patients with compassion, dignity, and good conduct. He emphasized that medical practice should not be driven by material gain, but by the pursuit of public service and the well-being of the people.

Speaking at the same ceremony, Hamdullah Nomani, Minister of Communications and Information Technology noted a decline in public trust toward some medical professionals, saying that despite the presence of many committed and ethical doctors, the behavior of a few motivated solely by financial gain has undermined patient confidence. He urged newly graduated specialists to serve with sincerity and restore public trust in Afghanistan’s healthcare system.

Meanwhile, Abdul Wali Sadiqi, the financial and administrative deputy minister of public health, advised graduates to remain committed to their profession, fulfill their responsibilities honestly, and serve the public with dedication. He stressed that efforts in national service should match those made in personal affairs.

In addition, Abdul Baqi Haqqani, head of the National Examinations Authority, highlighted that humans carry two fundamental responsibilities: worship of Allah and preservation of health, underscoring the vital role doctors play in safeguarding public health.

Health sector experts say Afghanistan now needs skilled and professional medical personnel more than ever, calling for increased investment in specialist training and healthcare infrastructure to meet the country’s growing needs.

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Afghan delegation heads to Turkey for medicine talks

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Naemullah Ayoubi, Director General of Drug and Health Products Regulation at Afghanistan’s Ministry of Public Health, has departed for Turkey on an official visit accompanied by a technical delegation.

The Ministry of Public Health said the delegation will hold meetings with officials from Turkey’s pharmaceutical regulatory authority and discuss a number of key issues related to the regulation of medicines and health products.

The delegation is also scheduled to visit several pharmaceutical manufacturing factories in Turkey.

According to the ministry, the visit aims to strengthen coordination between the two countries in the production and import of medicines, in order to ensure the availability of high-quality and affordable pharmaceuticals for people in Afghanistan in both the short and long term.

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