Health
No direct evidence COVID started in Wuhan lab: US intelligence report
U.S. intelligence agencies found no direct evidence that the COVID-19 pandemic stemmed from an incident at China’s Wuhan Institute of Virology, a report declassified on Friday said.
The four-page report by the Office of the Director of National Intelligence (ODNI) said the U.S. intelligence community still could not rule out the possibility that the virus came from a laboratory, however, and had not been able to discover the origins of the pandemic, Reuters reported.
“The Central Intelligence Agency and another agency remain unable to determine the precise origin of the COVID-19 pandemic, as both (natural and lab) hypotheses rely on significant assumptions or face challenges with conflicting reporting,” the ODNI report said.
The report said that while “extensive work” had been conducted on coronaviruses at the Wuhan institute (WIV), the agencies had not found evidence of a specific incident that could have caused the outbreak.
“We continue to have no indication that the WIV’s pre-pandemic research holdings included SARSCoV-2 or a close progenitor, nor any direct evidence that a specific research-related incident occurred involving WIV personnel before the pandemic that could have caused the COVID pandemic,” the report said.
The origins of the coronavirus pandemic have been a matter of furious debate in the United States almost since the first human cases were reported in Wuhan in late 2019.
U.S. President Joe Biden in March signed a bill declassifying information related to the origins of the pandemic.
Biden said at the time of signing that he shared Congress’ goal of releasing as much information as possible about the origin of COVID-19.
The debate was refueled by a Wall Street Journal report in February that the U.S. Energy Department had assessed with “low confidence” in a classified intelligence report that the pandemic most likely arose from a Chinese laboratory leak, an assessment Beijing denies.
FBI director Christopher Wray said on Feb. 28 his agency had assessed for some time that the origins of the pandemic were “most likely a potential lab incident” in the Chinese city of Wuhan. China said this claim had “no credibility whatsoever”.
As of March 20, four other U.S. agencies still judged that COVID-19 was likely the result of natural transmission, while two were undecided.
Health
Four-day polio vaccination campaign begins across Afghanistan
A nationwide polio vaccination campaign got underway across Afghanistan on Monday.
The four-day campaign aims to vaccinate around 12.77 million children under the age of five against polio.
Officials said the campaign is aimed at strengthening protection for children against polio and preventing the spread of the virus.
However, in the southern zone of the country, the polio vaccination campaign will begin one day later, on Tuesday, to ensure better implementation.
According to the information provided, Afghanistan has conducted one nationwide and two sub-national polio vaccination campaigns so far this year. The current campaign is the fourth of the year. In addition, localized campaigns and public awareness programs have also been carried out.
Officials said some environmental samples linked to the polio virus have tested positive. However, the Ministry of Public Health has not so far confirmed any human cases of polio.
According to officials, investigations into suspected cases are ongoing, and information on confirmed human cases will be shared once the assessments are completed and sufficient evidence is available.
Health
Afghanistan faces cancer treatment crisis
Spokesperson for the Ministry of Public Health, said dozens of cancer treatment centers are operating across the country.
The Afghanistan Cancer Foundation has raised concern over the rising number of cancer cases across the country, saying at least 1.5 million people are currently suffering from the disease.
According to figures released on Saturday, September 11, about 50,000 new cases are recorded annually. The figures are based on data from the Ministry of Public Health and international organizations.
Shafiq Shinwari, head of the Afghan Cancer Foundation, said in a recent interview that breast and uterine cancers are among the most common cancers in women, while lung, stomach, prostate and colon cancers are widespread among men.
He said cancer is the second-leading cause of death in Afghanistan after heart disease.
Cancer specialist Dr. Rahim Gul Darwish identified smoking and tobacco use, poor hygiene and unhealthy diets as major factors contributing to the spread of the disease.
Meanwhile, Sharafat Zaman Amarkhail, spokesperson for the Ministry of Public Health, said dozens of cancer treatment centers are operating across the country. However, he acknowledged serious shortages of modern equipment and facilities needed to provide comprehensive treatment.
The situation has been further aggravated by the departure of hundreds of medical specialists and healthcare workers since the Islamic Emirate returned to power, according to reports.
Afghan patients have also faced growing difficulties accessing treatment abroad. Many previously travelled to Pakistan for cancer care, but border closures and restrictions on Pakistani visas have made access more difficult.
Doctors say cancer patients require continuous treatment and regular specialist care, warning that shortages of facilities and restrictions on cross-border travel are increasing the risks for patients.
Health
Genetically modified pig kidney keeps man alive for record nine months
A genetically modified pig kidney has kept a 66-year-old man with end-stage kidney disease alive without dialysis for a record nine months, marking the first time a pig kidney has successfully served as a temporary “bridge” to a human kidney transplant.
Tim Andrews, from New Hampshire, was suffering from severe kidney failure caused by type 2 diabetes. Doctors said he had only a 9% chance of receiving a human kidney within five years, while facing a more than 40% risk of dying or being removed from the transplant waiting list.
Surgeons at Mass General Brigham in Massachusetts transplanted a kidney from a genetically modified Yucatan miniature pig named Wilma into Andrews in January 2025. The kidney functioned for 271 days, allowing him to remain free of dialysis before it began to fail.
After the pig kidney was removed, Andrews spent several months back on dialysis before receiving a kidney from a deceased human donor. The human kidney was functioning well after six months of follow-up, according to findings published in the medical journal The Lancet.
The transplant represents the longest dialysis-free survival recorded following a pig kidney xenotransplant in a living person. It is also the first documented case in which a patient successfully moved from a pig kidney transplant to a human kidney transplant.
Before the procedure, Wilma’s genome underwent 69 genetic modifications. Some changes were intended to reduce the risk of viruses being transmitted to humans, while others were designed to make the pig kidney more compatible with the human immune system and reduce the risk of rejection.
Andrews described the procedure as a “miracle”, saying it allowed him to return to everyday activities. He said he was able to cook, vacuum and take long walks with his dog.
The development could offer a potential solution to the severe shortage of human organs available for transplantation. Kidney transplantation provides the best survival prospects and quality of life for patients with end-stage kidney disease, but the global demand for donor kidneys far exceeds the supply.
Dr Leonardo Riella of Mass General Brigham said the shortage of organs remains “the greatest crisis” in transplantation. He said genetically modified animal organs could initially be used to help patients avoid dialysis while they wait for a human donor kidney and could eventually become a long-term treatment option if their safety and durability are established.
The pig kidney began showing damage to its blood vessels after about six months, eventually leading to organ failure and its removal nine months after transplantation.
Doctors found no new antibodies against human tissue following the procedure, suggesting the pig kidney did not make Andrews’ subsequent human transplant more difficult. No pig viruses or other pig pathogens were detected at any point.
The researchers cautioned that the result is based on a single patient with no comparison group. They said the outcome also depended on careful patient selection and intensive specialist care that may not be available in all settings.
Further clinical trials will be needed to determine whether genetically modified pig kidneys can safely and reliably be used as a bridge for other patients facing long waits for human organs.
The researchers said the case nevertheless provides new evidence that pig kidney transplantation could help address the global organ shortage and potentially offer patients a way to remain off dialysis while waiting for a human kidney.
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