Health
U.S. man recovering after ‘breakthrough’ pig-heart transplant
A U.S. man with terminal heart disease was implanted with a genetically modified pig heart in a first-of-its-kind surgery, and three days later the patient is doing well, his doctors reported on Monday.
The surgery, performed by a team at the University of Maryland Medicine, is among the first to demonstrate the feasibility of a pig-to-human heart transplant, a field made possible by new gene editing tools, Reuters reported.
If proven successful, scientists hope pig organs could help alleviate shortages of donor organs.
“This was a breakthrough surgery and brings us one step closer to solving the organ shortage crisis. There are simply not enough donor human hearts available to meet the long list of potential recipients,” Dr. Bartley Griffith, who surgically transplanted the pig heart into the patient, said in a statement.
“We are proceeding cautiously, but we are also optimistic that this first-in-the-world surgery will provide an important new option for patients in the future,” Griffith added.
According to the report for 57-year-old David Bennett of Maryland, the heart transplant was his last option.
“It was either die or do this transplant. I want to live. I know it’s a shot in the dark, but it’s my last choice,” Bennett said a day before his surgery, according to a statement released by the university.
To move ahead with the experimental surgery, the university obtained an emergency authorization from the U.S. Food and Drug Administration on New Year’s Eve through its compassionate use program.
“The FDA used our data and data on the experimental pig to authorize the transplant in an end-stage heart disease patient who had no other treatment options,” said Dr. Muhammad Mohiuddin, who heads the University’s program on xenotransplantation – transplanting animal organs into humans.
About 110,000 Americans are currently waiting for an organ transplant, and more than 6,000 patients die each year before getting one, according to organdonor.gov.
Bennett’s genetically modified pig heart was provided by Revivicor, a regenerative medicine company based in Blacksburg, Virginia. On the morning of the surgery, the transplant team removed the pig’s heart and placed it into a special device to preserve its function until the surgery, read the report.
Pigs have long been a tantalizing source of potential transplants because their organs are so similar to humans. A hog heart at the time of slaughter, for example, is about the size of an adult human heart.
Other organs from pigs being researched for transplantation into humans include kidneys, liver and lungs.
According to Reuters prior efforts at pig-to-human transplants have failed because of genetic differences that caused organ rejection or viruses that posed an infection risk.
Scientists have tackled that problem by editing away potentially harmful genes.
In the heart implanted in Bennett, three genes previously linked with organ rejection were “knocked out” of the donor pig, and six human genes linked with immune acceptance were inserted into the pig genome.
Researchers also deleted a pig gene to prevent excessive growth of the pig heart tissue.
The work was funded in part with a $15.7 million research grant to evaluate Revivicor’s genetically-modified pig hearts in baboon studies.
In addition to the genetic changes to the pig heart, Bennett received an experimental anti-rejection drug made by Kiniksa Pharmaceuticals based in Lexington, Mass.
Health
Health ministry holds meeting with envoys of international organizations in Kabul
Noor Jalal Jalali, Minister of Public Health of Afghanistan, held a meeting in Kabul with representatives of the World Health Organization, UNICEF, the World Bank, the Asian Development Bank, the European Union, the UK Foreign, Commonwealth and Development Office (FCDO), and other international organizations.
According to the ministry’s statement, representatives of these international organizations discussed the delivery of health and development services, improving the management of aid and resources in the health sector, integrating health facilities and aligning them with the new policy, providing health services in accordance with the Ministry of Public Health’s policy, strengthening the immunization and vaccination sector, delivering services based on priorities, and ensuring sustained coordination.
During the meeting, Jalali stressed the need for transparency and attention to the ministry’s priorities in order to enhance the effectiveness and impact of health services. He added that the delivery of health services must be carried out in line with the ministry’s policy and through better management of existing international assistance.
Referring to vaccination campaigns, he stated that the recent measles and polio vaccination campaign had been implemented very successfully, and emphasized that necessary preparations should be made for upcoming campaigns.
He also provided information regarding the review of the BPHS and EPHS health packages and the establishment of a standardized system through technical committees.
In this meeting, Edwin Ceniza, the WHO Representative for Afghanistan, reaffirmed the organization’s continued cooperation with the Ministry of Public Health and expressed appreciation to the ministry’s leadership for their tireless efforts to improve the health system.
Representatives of these organizations pledged to maintain effective and sustained coordination and to provide their services within the country in accordance with the policies and principles of the Ministry of Public Health.
Health
IEA health delegation travels to Turkey
Abdul Wali Haqqani, Deputy Minister for Health Services at the Ministry of Public Health of the Islamic Emirate of Afghanistan (IEA), has departed for Turkey on an official visit accompanied by a high-ranking delegation.
According to a statement released by the Health Ministry on Wednesday, the trip aims to acquire new health-sector expertise, assess Turkish medical and scientific institutions, meet with Turkish health and government officials, and strengthen bilateral cooperation.
During the visit, the delegation is scheduled to meet representatives from both public and private health sectors to support improvements in Afghanistan’s healthcare system and enhance coordination between the two countries, the statement added.
Health
Polio vaccination drive launches across 17 Afghan provinces
Officials say routine vaccination remains the most effective tool for eliminating polio and have urged families to fully cooperate with health teams during the campaign.
The Ministry of Public Health has announced the launch of a major anti-polio vaccination campaign, set to begin on Monday across 17 provinces of Afghanistan.
According to Sharafat Zaman, spokesperson for the ministry, the nationwide initiative will target 7.4 million children under the age of five, delivering vaccines door-to-door to prevent the spread of the poliovirus and safeguard children’s health.
Officials say routine vaccination remains the most effective tool for eliminating polio and have urged families to fully cooperate with health teams during the campaign.
This effort forms part of the government’s ongoing strategy to protect Afghanistan’s next generation from preventable diseases and strengthen public health across the country.
This comes after the World Health Organization (WHO) recently again classified the global spread of poliovirus as a Public Health Emergency of International Concern (PHEIC), warning that the disease remains endemic in only two countries — Afghanistan and Pakistan.
The decision followed the 43rd meeting of the Polio Emergency Committee under the International Health Regulations (IHR), which convened on 1 October 2025.
According to the Committee, Afghanistan reported four new wild poliovirus type 1 (WPV1) cases so far this year, compared to 24 in Pakistan.
The Afghan cases were detected in the country’s southern and eastern regions, where transmission remains intense despite ongoing vaccination efforts.
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