Health
Experts warn bird flu virus changing rapidly in largest ever outbreak
The virus causing record cases of avian influenza in birds across the world is changing rapidly, experts have warned, as calls increase for countries to vaccinate their poultry.
While emphasizing that the risk to humans remains low, the experts who spoke to AFP said that the surging number of bird flu cases in mammals was a cause for concern.
Since first emerging in 1996, the H5N1 avian influenza virus had previously been confined to mostly seasonal outbreaks.
But “something happened” in mid-2021 that made the group of viruses much more infectious, according to Richard Webby, the head of a World Health Organization collaborating center studying influenza in animals.
Since then, outbreaks have lasted all year round, spreading to new areas and leading to mass deaths among wild birds and tens of millions of poultry being culled, AFP reported.
Webby, who is a researcher at St Jude Children’s Research Hospital in the US city of Memphis, told AFP it was “absolutely” the largest outbreak of avian influenza the world had seen.
He led research, published this week in the journal Nature Communications, showing how the virus rapidly evolved as it spread from Europe into North America.
The study said the virus increased in virulence, which means it causes more dangerous disease, when it arrived in North America.
The researchers also infected a ferret with one of the new strains of bird flu.
They found an unexpectedly “huge” amount of the virus in its brain, Webby said, indicating it had caused more serious disease than previous strains.
Emphasizing that the risk in humans was still low, he said that “this virus is not being static, it’s changing”.
“That does increase the potential that even just by chance” the virus could “pick up genetic traits that allow it to be more of a human virus,” he said.
In rare cases, humans have contracted the sometimes deadly virus, usually after coming in close contact with infected birds.
The virus has also been detected in a soaring number of mammals, which Webby described as a “really, really troubling sign”.
Last week Chile said that nearly 9,000 sea lions, penguins, otters, porpoises and dolphins have died from bird flu along its north coast since the start of the year, AFP reported.
Most mammals are believed to have contracted the virus by eating an infected bird.
But Webby said that what “scares us the most” are indications from a Spanish mink farm, or among sea lions off South America, that the virus could be transmitting between mammals.
Ian Brown, virology head at the UK’s Animal and Plant Health Agency, said there has not yet been “clear evidence that this virus is easily sustaining in mammals.”
While the virus is changing to become “more efficient and more effective in birds,” it remains “unadapted to humans,” Brown told AFP.
Avian viruses bind to different receptors on the host cell than human viruses, Webby said.
It would take “two or three minor changes in one protein of the viruses” to become more adapted to humans, he said.
“That is what we’re really looking out for.”
Vaccinating poultry
One way to bring down the number of total bird flu cases, and therefore reduce the risk to humans, would be for countries to vaccinate their poultry, Webby said.
A few nations including China, Egypt and Vietnam have already held vaccination campaigns for poultry.
But many other countries have been reluctant due to import restrictions in some areas, and fears vaccinated birds that nonetheless get infected could slip through the net.
In April, the United States started testing several vaccine candidates for potential use on birds.
France recently said it hopes to start vaccinating poultry as early as autumn this year.
Christine Middlemiss, the UK’s chief veterinary officer, said that vaccinating poultry was not “a silver bullet because the virus changes constantly”.
But traditionally reluctant countries should consider vaccinating poultry more often, Middlemiss told AFP at an event at the UK’s embassy in Paris last week.
World Organisation for Animal Health director general Monique Eloit said that the issue of vaccinating poultry should be “on the table”.
After all, “everyone now knows that a pandemic is not just a fantasy — it could be a reality,” she added.
Noor Jalal Jalali, Minister of Public Health of Afghanistan, held a meeting in Kabul with representatives of the World Health Organization, UNICEF, the World Bank, the Asian Development Bank, the European Union, the UK Foreign, Commonwealth and Development Office (FCDO), and other international organizations.
According to the ministry’s statement, representatives of these international organizations discussed the delivery of health and development services, improving the management of aid and resources in the health sector, integrating health facilities and aligning them with the new policy, providing health services in accordance with the Ministry of Public Health’s policy, strengthening the immunization and vaccination sector, delivering services based on priorities, and ensuring sustained coordination.
During the meeting, Jalali stressed the need for transparency and attention to the ministry’s priorities in order to enhance the effectiveness and impact of health services. He added that the delivery of health services must be carried out in line with the ministry’s policy and through better management of existing international assistance.
Referring to vaccination campaigns, he stated that the recent measles and polio vaccination campaign had been implemented very successfully, and emphasized that necessary preparations should be made for upcoming campaigns.
He also provided information regarding the review of the BPHS and EPHS health packages and the establishment of a standardized system through technical committees.
In this meeting, Edwin Ceniza, the WHO Representative for Afghanistan, reaffirmed the organization’s continued cooperation with the Ministry of Public Health and expressed appreciation to the ministry’s leadership for their tireless efforts to improve the health system.
Representatives of these organizations pledged to maintain effective and sustained coordination and to provide their services within the country in accordance with the policies and principles of the Ministry of Public Health.
Abdul Wali Haqqani, Deputy Minister for Health Services at the Ministry of Public Health of the Islamic Emirate of Afghanistan (IEA), has departed for Turkey on an official visit accompanied by a high-ranking delegation.
According to a statement released by the Health Ministry on Wednesday, the trip aims to acquire new health-sector expertise, assess Turkish medical and scientific institutions, meet with Turkish health and government officials, and strengthen bilateral cooperation.
During the visit, the delegation is scheduled to meet representatives from both public and private health sectors to support improvements in Afghanistan’s healthcare system and enhance coordination between the two countries, the statement added.
Health
Polio vaccination drive launches across 17 Afghan provinces
Officials say routine vaccination remains the most effective tool for eliminating polio and have urged families to fully cooperate with health teams during the campaign.
The Ministry of Public Health has announced the launch of a major anti-polio vaccination campaign, set to begin on Monday across 17 provinces of Afghanistan.
According to Sharafat Zaman, spokesperson for the ministry, the nationwide initiative will target 7.4 million children under the age of five, delivering vaccines door-to-door to prevent the spread of the poliovirus and safeguard children’s health.
Officials say routine vaccination remains the most effective tool for eliminating polio and have urged families to fully cooperate with health teams during the campaign.
This effort forms part of the government’s ongoing strategy to protect Afghanistan’s next generation from preventable diseases and strengthen public health across the country.
This comes after the World Health Organization (WHO) recently again classified the global spread of poliovirus as a Public Health Emergency of International Concern (PHEIC), warning that the disease remains endemic in only two countries — Afghanistan and Pakistan.
The decision followed the 43rd meeting of the Polio Emergency Committee under the International Health Regulations (IHR), which convened on 1 October 2025.
According to the Committee, Afghanistan reported four new wild poliovirus type 1 (WPV1) cases so far this year, compared to 24 in Pakistan.
The Afghan cases were detected in the country’s southern and eastern regions, where transmission remains intense despite ongoing vaccination efforts.
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